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Mammalian G proteins and their cell type specific functions.
Wettschureck N, Offermanns S. Wettschureck N, et al. Physiol Rev. 2005 Oct;85(4):1159-204. doi: 10.1152/physrev.00003.2005. Physiol Rev. 2005. PMID: 16183910 Review.
Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes.
Wettschureck N, Rütten H, Zywietz A, Gehring D, Wilkie TM, Chen J, Chien KR, Offermanns S. Wettschureck N, et al. Nat Med. 2001 Nov;7(11):1236-40. doi: 10.1038/nm1101-1236. Nat Med. 2001. PMID: 11689889
Rho/Rho-kinase mediated signaling in physiology and pathophysiology.
Wettschureck N, Offermanns S. Wettschureck N, et al. J Mol Med (Berl). 2002 Oct;80(10):629-38. doi: 10.1007/s00109-002-0370-2. Epub 2002 Sep 7. J Mol Med (Berl). 2002. PMID: 12395147 Review.
G13 is an essential mediator of platelet activation in hemostasis and thrombosis.
Moers A, Nieswandt B, Massberg S, Wettschureck N, Grüner S, Konrad I, Schulte V, Aktas B, Gratacap MP, Simon MI, Gawaz M, Offermanns S. Moers A, et al. Nat Med. 2003 Nov;9(11):1418-22. doi: 10.1038/nm943. Epub 2003 Oct 5. Nat Med. 2003. PMID: 14528298
Mouse models to study G-protein-mediated signaling.
Wettschureck N, Moers A, Offermanns S. Wettschureck N, et al. Pharmacol Ther. 2004 Jan;101(1):75-89. doi: 10.1016/j.pharmthera.2003.10.005. Pharmacol Ther. 2004. PMID: 14729394 Review.
Heterotrimeric G proteins of the Gq/11 family are crucial for the induction of maternal behavior in mice.
Wettschureck N, Moers A, Hamalainen T, Lemberger T, Schütz G, Offermanns S. Wettschureck N, et al. Mol Cell Biol. 2004 Sep;24(18):8048-54. doi: 10.1128/MCB.24.18.8048-8054.2004. Mol Cell Biol. 2004. PMID: 15340067 Free PMC article.
G13-mediated signaling as a potential target for antiplatelet drugs.
Moers A, Wettschureck N, Offermanns S. Moers A, et al. Drug News Perspect. 2004 Oct;17(8):493-8. doi: 10.1358/dnp.2004.17.8.863692. Drug News Perspect. 2004. PMID: 15605108 Review.
Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice.
Wettschureck N, Moers A, Wallenwein B, Parlow AF, Maser-Gluth C, Offermanns S. Wettschureck N, et al. Mol Cell Biol. 2005 Mar;25(5):1942-8. doi: 10.1128/MCB.25.5.1942-1948.2005. Mol Cell Biol. 2005. PMID: 15713647 Free PMC article.
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