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Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Roland BP, Amrich CG, Kammerer CJ, Stuchul KA, Larsen SB, Rode S, Aslam AA, Heroux A, Wetzel R, VanDemark AP, Palladino MJ. Roland BP, et al. Among authors: wetzel r. Biochim Biophys Acta. 2015 Jan;1852(1):61-9. doi: 10.1016/j.bbadis.2014.10.010. Epub 2014 Oct 16. Biochim Biophys Acta. 2015. PMID: 25463631 Free PMC article.
β-hairpin-mediated nucleation of polyglutamine amyloid formation.
Kar K, Hoop CL, Drombosky KW, Baker MA, Kodali R, Arduini I, van der Wel PC, Horne WS, Wetzel R. Kar K, et al. Among authors: wetzel r. J Mol Biol. 2013 Apr 12;425(7):1183-97. doi: 10.1016/j.jmb.2013.01.016. Epub 2013 Jan 23. J Mol Biol. 2013. PMID: 23353826 Free PMC article.
540 results