Wexler EM - Search Results

1

Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling.

Rosen EY, Wexler EM, Versano R, Coppola G, Gao F, Winden KD, Oldham MC, Martens LH, Zhou P, Farese RV Jr, Geschwind DH. Rosen EY, et al. Among authors: wexler em. Neuron. 2011 Sep 22;71(6):1030-42. doi: 10.1016/j.neuron.2011.07.021. Epub 2011 Sep 21. Neuron. 2011. PMID: 21943601 Free PMC article.

2

Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways.

Wexler EM, Rosen E, Lu D, Osborn GE, Martin E, Raybould H, Geschwind DH. Wexler EM, et al. Sci Signal. 2011 Oct 4;4(193):ra65. doi: 10.1126/scisignal.2002282. Sci Signal. 2011. PMID: 21971039 Free PMC article.

3

DISC1: a schizophrenia gene with multiple personalities.

Wexler EM, Geschwind DH. Wexler EM, et al. Neuron. 2011 Nov 17;72(4):501-3. doi: 10.1016/j.neuron.2011.10.023. Neuron. 2011. PMID: 22099453 Free article.

4

RBFOX1 regulates both splicing and transcriptional networks in human neuronal development.

Fogel BL, Wexler E, Wahnich A, Friedrich T, Vijayendran C, Gao F, Parikshak N, Konopka G, Geschwind DH. Fogel BL, et al. Hum Mol Genet. 2012 Oct 1;21(19):4171-86. doi: 10.1093/hmg/dds240. Epub 2012 Jun 23. Hum Mol Genet. 2012. PMID: 22730494 Free PMC article.

5

Modeling the functional genomics of autism using human neurons.

Konopka G, Wexler E, Rosen E, Mukamel Z, Osborn GE, Chen L, Lu D, Gao F, Gao K, Lowe JK, Geschwind DH. Konopka G, et al. Mol Psychiatry. 2012 Feb;17(2):202-14. doi: 10.1038/mp.2011.60. Epub 2011 Jun 7. Mol Psychiatry. 2012. PMID: 21647150 Free PMC article.

6

Out FOXing Parkinson disease: where development meets neurodegeneration.

Wexler EM, Geschwind DH. Wexler EM, et al. PLoS Biol. 2007 Dec;5(12):e334. doi: 10.1371/journal.pbio.0050334. PLoS Biol. 2007. PMID: 18092892 Free PMC article.

7

Endogenous Wnt signaling maintains neural progenitor cell potency.

Wexler EM, Paucer A, Kornblum HI, Palmer TD, Geschwind DH. Wexler EM, et al. Stem Cells. 2009 May;27(5):1130-41. doi: 10.1002/stem.36. Stem Cells. 2009. PMID: 19418460 Free PMC article.

8

A quantitative framework to evaluate modeling of cortical development by neural stem cells.

Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. Stein JL, et al. Among authors: wexler em. Neuron. 2014 Jul 2;83(1):69-86. doi: 10.1016/j.neuron.2014.05.035. Neuron. 2014. PMID: 24991955 Free PMC article.

9

Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation.

Wexler EM, Geschwind DH, Palmer TD. Wexler EM, et al. Mol Psychiatry. 2008 Mar;13(3):285-92. doi: 10.1038/sj.mp.4002093. Epub 2007 Oct 30. Mol Psychiatry. 2008. PMID: 17968353

10

Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegeneration.

Coppola G, Choi SH, Santos MM, Miranda CJ, Tentler D, Wexler EM, Pandolfo M, Geschwind DH. Coppola G, et al. Among authors: wexler em. Neurobiol Dis. 2006 May;22(2):302-11. doi: 10.1016/j.nbd.2005.11.014. Epub 2006 Jan 25. Neurobiol Dis. 2006. PMID: 16442805 Free PMC article.

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