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Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2.
Cancer Cell. 2016 Apr 11;29(4):477-493. doi: 10.1016/j.ccell.2016.02.010. Epub 2016 Mar 17.
Cancer Cell. 2016.
PMID: 26996308
Free article.
Shining LIGHT on functional promiscuity in the TNF and TNFR superfamilies.
Whalen DM, Hymowitz SG.
Whalen DM, et al.
Structure. 2014 Sep 2;22(9):1221-1222. doi: 10.1016/j.str.2014.08.003.
Structure. 2014.
PMID: 25185824
Free article.
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Kinase domain dimerization drives RIPK3-dependent necroptosis.
Raju S, Whalen DM, Mengistu M, Swanson C, Quinn JG, Taylor SS, Webster JD, Newton K, Shaw AS.
Raju S, et al. Among authors: whalen dm.
Sci Signal. 2018 Aug 21;11(544):eaar2188. doi: 10.1126/scisignal.aar2188.
Sci Signal. 2018.
PMID: 30131368
Free PMC article.
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Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS.
Schulze CJ, Seamon KJ, Zhao Y, Yang YC, Cregg J, Kim D, Tomlinson A, Choy TJ, Wang Z, Sang B, Pourfarjam Y, Lucas J, Cuevas-Navarro A, Ayala-Santos C, Vides A, Li C, Marquez A, Zhong M, Vemulapalli V, Weller C, Gould A, Whalen DM, Salvador A, Milin A, Saldajeno-Concar M, Dinglasan N, Chen A, Evans J, Knox JE, Koltun ES, Singh M, Nichols R, Wildes D, Gill AL, Smith JAM, Lito P.
Schulze CJ, et al. Among authors: whalen dm.
Science. 2023 Aug 18;381(6659):794-799. doi: 10.1126/science.adg9652. Epub 2023 Aug 17.
Science. 2023.
PMID: 37590355
Free PMC article.
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Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis.
Graham SC, Bahar MW, Cooray S, Chen RA, Whalen DM, Abrescia NG, Alderton D, Owens RJ, Stuart DI, Smith GL, Grimes JM.
Graham SC, et al. Among authors: whalen dm.
PLoS Pathog. 2008 Aug 15;4(8):e1000128. doi: 10.1371/journal.ppat.1000128.
PLoS Pathog. 2008.
PMID: 18704168
Free PMC article.
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Structural insights into proteoglycan-shaped Hedgehog signaling.
Whalen DM, Malinauskas T, Gilbert RJ, Siebold C.
Whalen DM, et al.
Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16420-5. doi: 10.1073/pnas.1310097110. Epub 2013 Sep 23.
Proc Natl Acad Sci U S A. 2013.
PMID: 24062467
Free PMC article.
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Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling.
Nachtergaele S, Whalen DM, Mydock LK, Zhao Z, Malinauskas T, Krishnan K, Ingham PW, Covey DF, Siebold C, Rohatgi R.
Nachtergaele S, et al. Among authors: whalen dm.
Elife. 2013 Oct 29;2:e01340. doi: 10.7554/eLife.01340.
Elife. 2013.
PMID: 24171105
Free PMC article.
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The grandmother role as experienced by lesbian women.
Whalen DM, Bigner JJ, Barber CE.
Whalen DM, et al.
J Women Aging. 2000;12(3-4):39-57. doi: 10.1300/J074v12n03_04.
J Women Aging. 2000.
PMID: 11151354
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