Wheaton WW - Search Results

1

Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness.

Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, Nickoloff BJ, Topczewski J, Hendrix MJ. Topczewska JM, et al. Among authors: wheaton ww. Nat Med. 2006 Aug;12(8):925-32. doi: 10.1038/nm1448. Epub 2006 Jul 30. Nat Med. 2006. PMID: 16892036

2

Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells.

Postovit LM, Margaryan NV, Seftor EA, Kirschmann DA, Lipavsky A, Wheaton WW, Abbott DE, Seftor RE, Hendrix MJ. Postovit LM, et al. Among authors: wheaton ww. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4329-34. doi: 10.1073/pnas.0800467105. Epub 2008 Mar 11. Proc Natl Acad Sci U S A. 2008. PMID: 18334633 Free PMC article.

3

Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment.

Seftor EA, Brown KM, Chin L, Kirschmann DA, Wheaton WW, Protopopov A, Feng B, Balagurunathan Y, Trent JM, Nickoloff BJ, Seftor RE, Hendrix MJ. Seftor EA, et al. Among authors: wheaton ww. Cancer Res. 2005 Nov 15;65(22):10164-9. doi: 10.1158/0008-5472.CAN-05-2497. Cancer Res. 2005. PMID: 16288000

4

Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration.

Postovit LM, Abbott DE, Payne SL, Wheaton WW, Margaryan NV, Sullivan R, Jansen MK, Csiszar K, Hendrix MJ, Kirschmann DA. Postovit LM, et al. Among authors: wheaton ww. J Cell Biochem. 2008 Apr 1;103(5):1369-78. doi: 10.1002/jcb.21517. J Cell Biochem. 2008. PMID: 17685448

5

Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership.

Bailey CM, Khalkhali-Ellis Z, Kondo S, Margaryan NV, Seftor RE, Wheaton WW, Amir S, Pins MR, Schutte BC, Hendrix MJ. Bailey CM, et al. Among authors: wheaton ww. J Biol Chem. 2005 Oct 7;280(40):34210-7. doi: 10.1074/jbc.M503523200. Epub 2005 Jul 26. J Biol Chem. 2005. PMID: 16049006 Free PMC article.

6

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis.

Wheaton WW, Weinberg SE, Hamanaka RB, Soberanes S, Sullivan LB, Anso E, Glasauer A, Dufour E, Mutlu GM, Budigner GS, Chandel NS. Wheaton WW, et al. Elife. 2014 May 13;3:e02242. doi: 10.7554/eLife.02242. Elife. 2014. PMID: 24843020 Free PMC article.

7

Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.

Patra KC, Wang Q, Bhaskar PT, Miller L, Wang Z, Wheaton W, Chandel N, Laakso M, Muller WJ, Allen EL, Jha AK, Smolen GA, Clasquin MF, Robey B, Hay N. Patra KC, et al. Cancer Cell. 2013 Aug 12;24(2):213-228. doi: 10.1016/j.ccr.2013.06.014. Epub 2013 Aug 1. Cancer Cell. 2013. PMID: 23911236 Free PMC article.

8

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

Mullen AR, Wheaton WW, Jin ES, Chen PH, Sullivan LB, Cheng T, Yang Y, Linehan WM, Chandel NS, DeBerardinis RJ. Mullen AR, et al. Among authors: wheaton ww. Nature. 2011 Nov 20;481(7381):385-8. doi: 10.1038/nature10642. Nature. 2011. PMID: 22101431 Free PMC article.

9

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.

Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS. Weinberg F, et al. Among authors: wheaton ww. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8788-93. doi: 10.1073/pnas.1003428107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421486 Free PMC article.

10

Hypoxia. 2. Hypoxia regulates cellular metabolism.

Wheaton WW, Chandel NS. Wheaton WW, et al. Am J Physiol Cell Physiol. 2011 Mar;300(3):C385-93. doi: 10.1152/ajpcell.00485.2010. Epub 2010 Dec 1. Am J Physiol Cell Physiol. 2011. PMID: 21123733 Free PMC article. Review.

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