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In vitro and in vivo evaluation of insulin-producing beta TC6-F7 cells in microcapsules.
Zhou D, Sun AM, Li X, Mamujee SN, Vacek I, Georgiou J, Wheeler MB. Zhou D, et al. Am J Physiol. 1998 May;274(5):C1356-62. doi: 10.1152/ajpcell.1998.274.5.C1356. Am J Physiol. 1998. PMID: 9612223
Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.
Pederson RA, Satkunarajah M, McIntosh CH, Scrocchi LA, Flamez D, Schuit F, Drucker DJ, Wheeler MB. Pederson RA, et al. Diabetes. 1998 Jul;47(7):1046-52. doi: 10.2337/diabetes.47.7.1046. Diabetes. 1998. PMID: 9648827
Genetic engineering of glucose-stimulated insulin secretion in Chinese hamster ovary cells.
Kintsurashvili E, Zhou D, Wheeler MB, Vacek I, Sun AM. Kintsurashvili E, et al. Artif Cells Blood Substit Immobil Biotechnol. 1998 Jul;26(4):329-40. doi: 10.3109/10731199809117675. Artif Cells Blood Substit Immobil Biotechnol. 1998. PMID: 9663332
Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs.
Sandhu H, Wiesenthal SR, MacDonald PE, McCall RH, Tchipashvili V, Rashid S, Satkunarajah M, Irwin DM, Shi ZQ, Brubaker PL, Wheeler MB, Vranic M, Efendic S, Giacca A. Sandhu H, et al. Diabetes. 1999 May;48(5):1045-53. doi: 10.2337/diabetes.48.5.1045. Diabetes. 1999. PMID: 10331409
Characterization of glucagon-like peptide-1 receptor-binding determinants.
Xiao Q, Jeng W, Wheeler MB. Xiao Q, et al. J Mol Endocrinol. 2000 Dec;25(3):321-35. doi: 10.1677/jme.0.0250321. J Mol Endocrinol. 2000. PMID: 11116211
Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion.
MacDonald PE, Ha XF, Wang J, Smukler SR, Sun AM, Gaisano HY, Salapatek AM, Backx PH, Wheeler MB. MacDonald PE, et al. Mol Endocrinol. 2001 Aug;15(8):1423-35. doi: 10.1210/mend.15.8.0685. Mol Endocrinol. 2001. PMID: 11463864
Ca(2+) influx and cAMP elevation overcame botulinum toxin A but not tetanus toxin inhibition of insulin exocytosis.
Huang X, Kang YH, Pasyk EA, Sheu L, Wheeler MB, Trimble WS, Salapatek A, Gaisano HY. Huang X, et al. Am J Physiol Cell Physiol. 2001 Sep;281(3):C740-50. doi: 10.1152/ajpcell.2001.281.3.C740. Am J Physiol Cell Physiol. 2001. PMID: 11502551
Syntaxin-3 and syntaxin-1A inhibit L-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines.
Kang Y, Huang X, Pasyk EA, Ji J, Holz GG, Wheeler MB, Tsushima RG, Gaisano HY. Kang Y, et al. Diabetologia. 2002 Feb;45(2):231-41. doi: 10.1007/s00125-001-0718-0. Diabetologia. 2002. PMID: 11935155 Free PMC article.
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