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Nephrotoxicity of nonsteroidal anti-inflammatory drugs: physiologic foundations and clinical implications.
Whelton A. Whelton A. Am J Med. 1999 May 31;106(5B):13S-24S. doi: 10.1016/s0002-9343(99)00113-8. Am J Med. 1999. PMID: 10390124 Review.
This is a matter of considerable public health concern, in that some 12 million US citizens are concurrently treated with NSAIDs and antihypertensive drugs. ...
This is a matter of considerable public health concern, in that some 12 million US citizens are concurrently treated with NSAIDs and …
Treatment of gram-negative infections in patients with renal impairment: new alternatives to aminoglycosides.
Whelton A. Whelton A. J Clin Pharmacol. 1988 Oct;28(10):866-78. doi: 10.1002/j.1552-4604.1988.tb03109.x. J Clin Pharmacol. 1988. PMID: 3065360 Review.
The antimicrobial spectrum of aztreonam, a monobactam, closely resembles that of aminoglycosides. Imipenem, a carbapenem, is a broad spectrum antibiotic with activity against gram-negative aerobes as well as gram-positive aerobes and many anaerobes. ...
The antimicrobial spectrum of aztreonam, a monobactam, closely resembles that of aminoglycosides. Imipenem, a carbapenem, is …
Drug-induced nephrotoxicity.
Piepho R, Whelton A, Mayor G, Neu H, Laddu A. Piepho R, et al. Among authors: whelton a. J Clin Pharmacol. 1991 Sep;31(9):785-91. doi: 10.1002/j.1552-4604.1991.tb01911.x. J Clin Pharmacol. 1991. PMID: 1804859 No abstract available.
Cholestyramine-induced hyperchloremic metabolic acidosis.
Scheel PJ Jr, Whelton A, Rossiter K, Watson A. Scheel PJ Jr, et al. Among authors: whelton a. J Clin Pharmacol. 1992 Jun;32(6):536-8. doi: 10.1177/009127009203200608. J Clin Pharmacol. 1992. PMID: 1634640 Review.
Cholestyramine is a nonabsorbable anion exchange resin that is used predominantly for the treatment of hypercholesterolemia in adults and the management of acute diarrhea in children. ...The authors recommend that patients taking cholestyramine who have concomitant renal i …
Cholestyramine is a nonabsorbable anion exchange resin that is used predominantly for the treatment of hypercholesterolemia in adults …
Renal effects of over-the-counter analgesics.
Whelton A. Whelton A. J Clin Pharmacol. 1995 May;35(5):454-63. doi: 10.1002/j.1552-4604.1995.tb04088.x. J Clin Pharmacol. 1995. PMID: 7657844 Review.
Recent case reports have shown that over-the-counter (OTC) analgesics, which are generally considered to be a safe treatment for minor aches and pains and fever, may cause adverse renal effects. ...Acetaminophen lacks significant peripheral prostaglandin inhibition and may …
Recent case reports have shown that over-the-counter (OTC) analgesics, which are generally considered to be a safe treatment for mino …
Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.
Bender WL, Whelton A, Beschorner WE, Darwish MO, Hall-Craggs M, Solez K. Bender WL, et al. Among authors: whelton a. Am J Med. 1984 Jun;76(6):1006-12. doi: 10.1016/0002-9343(84)90849-0. Am J Med. 1984. PMID: 6375363
Hypertension and renal dysfunction in bone marrow transplant recipients.
Kone BC, Whelton A, Santos G, Saral R, Watson AJ. Kone BC, et al. Among authors: whelton a. Q J Med. 1988 Dec;69(260):985-95. Q J Med. 1988. PMID: 3270085 Clinical Trial.
., aminoglycoside antibiotics) play a major role as shown by the high incidence of renal and electrolyte disorders in patients treated with cyclophosphamide alone....
., aminoglycoside antibiotics) play a major role as shown by the high incidence of renal and electrolyte disorders in patients treate …
Once-daily lisinopril compared with twice-daily captopril in the treatment of mild to moderate hypertension: assessment of office and ambulatory blood pressures.
Whelton A, Miller WE, Dunne B Jr, Hait HI, Tresznewsky ON. Whelton A, et al. J Clin Pharmacol. 1990 Dec;30(12):1074-80. doi: 10.1002/j.1552-4604.1990.tb01848.x. J Clin Pharmacol. 1990. PMID: 2177062 Clinical Trial.
Doses of 10, 20, and 40 mg once-daily lisinopril or 25, 50, and 100 mg bid captopril were increased at biweekly intervals until patients responded to treatment, as defined by a decrease in office diastolic pressure to less than 90 mm Hg or at least a 10 mm Hg decrea …
Doses of 10, 20, and 40 mg once-daily lisinopril or 25, 50, and 100 mg bid captopril were increased at biweekly intervals until patients res …
Ambulatory monitoring of blood pressure.
Whelton A. Whelton A. Hosp Pract (Off Ed). 1991 Mar;26 Suppl 2:13-9; discussion 31-3. doi: 10.1080/21548331.1991.11704273. Hosp Pract (Off Ed). 1991. PMID: 1899417
Thus, a determination of 24-hour antihypertensive control and comparison of the efficacy of drug regimens can help to prevent undertreatment as well as overtreatment....
Thus, a determination of 24-hour antihypertensive control and comparison of the efficacy of drug regimens can help to prevent undertr …
24-hour activity of lisinopril: clinical advantage in blood pressure control.
Whelton A. Whelton A. Cardiology. 1991;79 Suppl 1:10-5. doi: 10.1159/000174901. Cardiology. 1991. PMID: 1655261 Clinical Trial.
We have conducted a multicentre study in patients with mild to moderate hypertension. Lisinopril monotherapy, 10, 20, or 40 mg once daily (n = 35), was compared with captopril monotherapy, 25, 50, or 100 mg twice daily (n = 35). ...
We have conducted a multicentre study in patients with mild to moderate hypertension. Lisinopril monotherapy, 10, 20, or 40 mg once d …
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