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IQGAP1 and its binding proteins control diverse biological functions.
White CD, Erdemir HH, Sacks DB. White CD, et al. Cell Signal. 2012 Apr;24(4):826-34. doi: 10.1016/j.cellsig.2011.12.005. Epub 2011 Dec 11. Cell Signal. 2012. PMID: 22182509 Free PMC article. Review.
MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation.
McNulty DE, Li Z, White CD, Sacks DB, Annan RS. McNulty DE, et al. Among authors: white cd. J Biol Chem. 2011 Apr 29;286(17):15010-21. doi: 10.1074/jbc.M111.227694. Epub 2011 Feb 24. J Biol Chem. 2011. PMID: 21349850 Free PMC article.
IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance.
White CD, Li Z, Dillon DA, Sacks DB. White CD, et al. J Biol Chem. 2011 Aug 26;286(34):29734-47. doi: 10.1074/jbc.M111.220939. Epub 2011 Jul 1. J Biol Chem. 2011. PMID: 21724847 Free PMC article.
Salmonella enterica serotype Typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAPK signalling.
Kim H, White CD, Li Z, Sacks DB. Kim H, et al. Among authors: white cd. Biochem J. 2011 Dec 15;440(3):309-18. doi: 10.1042/BJ20110419. Biochem J. 2011. PMID: 21851337 Free PMC article.
IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton.
Kim H, White CD, Sacks DB. Kim H, et al. Among authors: white cd. FEBS Lett. 2011 Mar 9;585(5):723-9. doi: 10.1016/j.febslet.2011.01.041. Epub 2011 Feb 2. FEBS Lett. 2011. PMID: 21295032 Free PMC article. Review.
Calmodulin binds HER2 and modulates HER2 signaling.
White CD, Li Z, Sacks DB. White CD, et al. Biochim Biophys Acta. 2011 May;1813(5):1074-82. doi: 10.1016/j.bbamcr.2010.12.016. Epub 2010 Dec 24. Biochim Biophys Acta. 2011. PMID: 21185879 Free PMC article.
IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.
White CD, Khurana H, Gnatenko DV, Li Z, Odze RD, Sacks DB, Schmidt VA. White CD, et al. BMC Gastroenterol. 2010 Oct 26;10:125. doi: 10.1186/1471-230X-10-125. BMC Gastroenterol. 2010. PMID: 20977743 Free PMC article.
IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis.
White CD, Brown MD, Sacks DB. White CD, et al. FEBS Lett. 2009 Jun 18;583(12):1817-24. doi: 10.1016/j.febslet.2009.05.007. Epub 2009 May 9. FEBS Lett. 2009. PMID: 19433088 Free PMC article. Review.
Regulation of MAP kinase signaling by calcium.
White CD, Sacks DB. White CD, et al. Methods Mol Biol. 2010;661:151-65. doi: 10.1007/978-1-60761-795-2_9. Methods Mol Biol. 2010. PMID: 20811982
Using phospho-motif antibodies to determine kinase substrates.
White CD, Toker A. White CD, et al. Curr Protoc Mol Biol. 2013 Jan;Chapter 18:Unit 18.20.. doi: 10.1002/0471142727.mb1820s101. Curr Protoc Mol Biol. 2013. PMID: 23288461
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