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Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment.
Whitson JA, Johnson R, Wang L, Bammler TK, Imai SI, Zhang H, Fredrickson J, Latorre-Esteves E, Bitto A, MacCoss MJ, Rabinovitch PS. Whitson JA, et al. Geroscience. 2022 Jun;44(3):1621-1639. doi: 10.1007/s11357-022-00564-w. Epub 2022 Apr 13. Geroscience. 2022. PMID: 35416576 Free PMC article.
An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice.
Tsantilas KA, Cleghorn WM, Bisbach CM, Whitson JA, Hass DT, Robbings BM, Sadilek M, Linton JD, Rountree AM, Valencia AP, Sweetwyne MT, Campbell MD, Zhang H, Jankowski CSR, Sweet IR, Marcinek DJ, Rabinovitch PS, Hurley JB. Tsantilas KA, et al. Among authors: whitson ja. Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):20. doi: 10.1167/iovs.62.14.20. Invest Ophthalmol Vis Sci. 2021. PMID: 34797906 Free PMC article.
A replication-linked mutational gradient drives somatic mutation accumulation and influences germline polymorphisms and genome composition in mitochondrial DNA.
Sanchez-Contreras M, Sweetwyne MT, Kohrn BF, Tsantilas KA, Hipp MJ, Schmidt EK, Fredrickson J, Whitson JA, Campbell MD, Rabinovitch PS, Marcinek DJ, Kennedy SR. Sanchez-Contreras M, et al. Among authors: whitson ja. Nucleic Acids Res. 2021 Nov 8;49(19):11103-11118. doi: 10.1093/nar/gkab901. Nucleic Acids Res. 2021. PMID: 34614167 Free PMC article.
14 results