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Rescue of ligand binding of a mutant IGF-I receptor by complementation.
Chakravarty A, Hinrichsen J, Whittaker L, Whittaker J. Chakravarty A, et al. Among authors: whittaker l, whittaker j. Biochem Biophys Res Commun. 2005 May 27;331(1):74-7. doi: 10.1016/j.bbrc.2005.03.122. Biochem Biophys Res Commun. 2005. PMID: 15845360
How insulin engages its primary binding site on the insulin receptor.
Menting JG, Whittaker J, Margetts MB, Whittaker LJ, Kong GK, Smith BJ, Watson CJ, Záková L, Kletvíková E, Jiráček J, Chan SJ, Steiner DF, Dodson GG, Brzozowski AM, Weiss MA, Ward CW, Lawrence MC. Menting JG, et al. Among authors: whittaker j, whittaker lj. Nature. 2013 Jan 10;493(7431):241-5. doi: 10.1038/nature11781. Nature. 2013. PMID: 23302862 Free PMC article.
Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists.
Smith BJ, Huang K, Kong G, Chan SJ, Nakagawa S, Menting JG, Hu SQ, Whittaker J, Steiner DF, Katsoyannis PG, Ward CW, Weiss MA, Lawrence MC. Smith BJ, et al. Among authors: whittaker j. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6771-6. doi: 10.1073/pnas.1001813107. Epub 2010 Mar 26. Proc Natl Acad Sci U S A. 2010. PMID: 20348418 Free PMC article.
Aromatic anchor at an invariant hormone-receptor interface: function of insulin residue B24 with application to protein design.
Pandyarajan V, Smith BJ, Phillips NB, Whittaker L, Cox GP, Wickramasinghe N, Menting JG, Wan ZL, Whittaker J, Ismail-Beigi F, Lawrence MC, Weiss MA. Pandyarajan V, et al. Among authors: whittaker l, whittaker j. J Biol Chem. 2014 Dec 12;289(50):34709-27. doi: 10.1074/jbc.M114.608562. Epub 2014 Oct 10. J Biol Chem. 2014. PMID: 25305014 Free PMC article.
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