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380 results
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Specific prediction of clinical QT prolongation by kinetic image cytometry in human stem cell derived cardiomyocytes.
Pfeiffer ER, Vega R, McDonough PM, Price JH, Whittaker R. Pfeiffer ER, et al. Among authors: whittaker r. J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:263-73. doi: 10.1016/j.vascn.2016.04.007. Epub 2016 Apr 16. J Pharmacol Toxicol Methods. 2016. PMID: 27095424
Pim-1 kinase protects mitochondrial integrity in cardiomyocytes.
Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, Gustafsson AB, Miyamoto S, Glembotski CC, Gottlieb RA, Brown JH, Sussman MA. Borillo GA, et al. Among authors: whittaker r. Circ Res. 2010 Apr 16;106(7):1265-74. doi: 10.1161/CIRCRESAHA.109.212035. Epub 2010 Mar 4. Circ Res. 2010. PMID: 20203306 Free PMC article.
High throughput measurement of Ca²⁺ dynamics for drug risk assessment in human stem cell-derived cardiomyocytes by kinetic image cytometry.
Cerignoli F, Charlot D, Whittaker R, Ingermanson R, Gehalot P, Savchenko A, Gallacher DJ, Towart R, Price JH, McDonough PM, Mercola M. Cerignoli F, et al. Among authors: whittaker r. J Pharmacol Toxicol Methods. 2012 Nov-Dec;66(3):246-56. doi: 10.1016/j.vascn.2012.08.167. Epub 2012 Aug 25. J Pharmacol Toxicol Methods. 2012. PMID: 22926323 Free PMC article.
High Throughput Measurement of Ca++ Dynamics in Human Stem Cell-Derived Cardiomyocytes by Kinetic Image Cytometery: A Cardiac Risk Assessment Characterization Using a Large Panel of Cardioactive and Inactive Compounds.
Lu HR, Whittaker R, Price JH, Vega R, Pfeiffer ER, Cerignoli F, Towart R, Gallacher DJ. Lu HR, et al. Among authors: whittaker r. Toxicol Sci. 2015 Dec;148(2):503-16. doi: 10.1093/toxsci/kfv201. Epub 2015 Sep 9. Toxicol Sci. 2015. PMID: 26358003
Quantification of hormone sensitive lipase phosphorylation and colocalization with lipid droplets in murine 3T3L1 and human subcutaneous adipocytes via automated digital microscopy and high-content analysis.
McDonough PM, Ingermanson RS, Loy PA, Koon ED, Whittaker R, Laris CA, Hilton JM, Nicoll JB, Buehrer BM, Price JH. McDonough PM, et al. Among authors: whittaker r. Assay Drug Dev Technol. 2011 Jun;9(3):262-80. doi: 10.1089/adt.2010.0302. Epub 2010 Dec 27. Assay Drug Dev Technol. 2011. PMID: 21186937 Free PMC article.
Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis.
McDonough PM, Maciejewski-Lenoir D, Hartig SM, Hanna RA, Whittaker R, Heisel A, Nicoll JB, Buehrer BM, Christensen K, Mancini MG, Mancini MA, Edwards DP, Price JH. McDonough PM, et al. Among authors: whittaker r. PLoS One. 2013;8(2):e55511. doi: 10.1371/journal.pone.0055511. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405163 Free PMC article.
Identification of MicroRNAs that control lipid droplet formation and growth in hepatocytes via high-content screening.
Whittaker R, Loy PA, Sisman E, Suyama E, Aza-Blanc P, Ingermanson RS, Price JH, McDonough PM. Whittaker R, et al. J Biomol Screen. 2010 Aug;15(7):798-805. doi: 10.1177/1087057110374991. Epub 2010 Jul 16. J Biomol Screen. 2010. PMID: 20639500
PHLPP-1 negatively regulates Akt activity and survival in the heart.
Miyamoto S, Purcell NH, Smith JM, Gao T, Whittaker R, Huang K, Castillo R, Glembotski CC, Sussman MA, Newton AC, Brown JH. Miyamoto S, et al. Among authors: whittaker r. Circ Res. 2010 Aug 20;107(4):476-84. doi: 10.1161/CIRCRESAHA.109.215020. Epub 2010 Jun 24. Circ Res. 2010. PMID: 20576936 Free PMC article.
Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6.
Martindale JJ, Fernandez R, Thuerauf D, Whittaker R, Gude N, Sussman MA, Glembotski CC. Martindale JJ, et al. Among authors: whittaker r. Circ Res. 2006 May 12;98(9):1186-93. doi: 10.1161/01.RES.0000220643.65941.8d. Epub 2006 Apr 6. Circ Res. 2006. PMID: 16601230
Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion.
Jin JK, Whittaker R, Glassy MS, Barlow SB, Gottlieb RA, Glembotski CC. Jin JK, et al. Among authors: whittaker r. Am J Physiol Heart Circ Physiol. 2008 Jan;294(1):H337-44. doi: 10.1152/ajpheart.00881.2007. Epub 2007 Nov 9. Am J Physiol Heart Circ Physiol. 2008. PMID: 17993600
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