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Defining the optimal dose of rifapentine for pulmonary tuberculosis: Exposure-response relations from two phase II clinical trials.
Savic RM, Weiner M, MacKenzie WR, Engle M, Whitworth WC, Johnson JL, Nsubuga P, Nahid P, Nguyen NV, Peloquin CA, Dooley KE, Dorman SE; Tuberculosis Trials Consortium of the Centers for Disease Control and Prevention. Savic RM, et al. Among authors: Whitworth WC. Version 2. Clin Pharmacol Ther. 2017 Aug;102(2):321-331. doi: 10.1002/cpt.634. Epub 2017 Mar 2. Clin Pharmacol Ther. 2017. PMID: 28124478 Free PMC article. Clinical Trial.
Population Pharmacokinetics of Pyrazinamide in Patients with Tuberculosis.
Alsultan A, Savic R, Dooley KE, Weiner M, Whitworth W, Mac Kenzie WR, Peloquin CA; Tuberculosis Trials Consortium. Alsultan A, et al. Among authors: Whitworth W. Antimicrob Agents Chemother. 2017 May 24;61(6):e02625-16. doi: 10.1128/AAC.02625-16. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28289033 Free PMC article.
Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial.
Sigal GB, Segal MR, Mathew A, Jarlsberg L, Wang M, Barbero S, Small N, Haynesworth K, Davis JL, Weiner M, Whitworth WC, Jacobs J, Schorey J, Lewinsohn DM, Nahid P. Sigal GB, et al. Among authors: Whitworth WC. EBioMedicine. 2017 Nov;25:112-121. doi: 10.1016/j.ebiom.2017.10.018. Epub 2017 Oct 24. EBioMedicine. 2017. PMID: 29100778 Free PMC article. Clinical Trial.
Xpert MTB/RIF Assay Shows Faster Clearance of Mycobacterium tuberculosis DNA with Higher Levels of Rifapentine Exposure.
Jayakumar A, Savic RM, Everett CK, Benator D, Alland D, Heilig CM, Weiner M, Friedrich SO, Martinson NA, Kerrigan A, Zamudio C, Goldberg SV, Whitworth WC, Davis JL, Nahid P. Jayakumar A, et al. Among authors: Whitworth WC. J Clin Microbiol. 2016 Dec;54(12):3028-3033. doi: 10.1128/JCM.01313-16. Epub 2016 Oct 12. J Clin Microbiol. 2016. PMID: 27733634 Free PMC article. Clinical Trial.
Variability of the QuantiFERON®-TB gold in-tube test using automated and manual methods.
Whitworth WC, Goodwin DJ, Racster L, West KB, Chuke SO, Daniels LJ, Campbell BH, Bohanon J, Jaffar AT, Drane W, Sjoberg PA, Mazurek GH. Whitworth WC, et al. PLoS One. 2014 Jan 23;9(1):e86721. doi: 10.1371/journal.pone.0086721. eCollection 2014. PLoS One. 2014. PMID: 24466211 Free PMC article.
Multiple cytokines are released when blood from patients with tuberculosis is stimulated with Mycobacterium tuberculosis antigens.
Kellar KL, Gehrke J, Weis SE, Mahmutovic-Mayhew A, Davila B, Zajdowicz MJ, Scarborough R, LoBue PA, Lardizabal AA, Daley CL, Reves RR, Bernardo J, Campbell BH, Whitworth WC, Mazurek GH. Kellar KL, et al. Among authors: Whitworth WC. PLoS One. 2011;6(11):e26545. doi: 10.1371/journal.pone.0026545. Epub 2011 Nov 21. PLoS One. 2011. PMID: 22132075 Free PMC article.
Within-subject interlaboratory variability of QuantiFERON-TB gold in-tube tests.
Whitworth WC, Hamilton LR, Goodwin DJ, Barrera C, West KB, Racster L, Daniels LJ, Chuke SO, Campbell BH, Bohanon J, Jaffar AT, Drane W, Maserang D, Mazurek GH. Whitworth WC, et al. PLoS One. 2012;7(9):e43790. doi: 10.1371/journal.pone.0043790. Epub 2012 Sep 6. PLoS One. 2012. PMID: 22970142 Free PMC article.
Tuberculin Skin Tests versus Interferon-Gamma Release Assays in Tuberculosis Screening among Immigrant Visa Applicants.
Chuke SO, Yen NT, Laserson KF, Phuoc NH, Trinh NA, Nhung DT, Mai VT, Qui AD, Hai HH, Loan le TH, Jones WG, Whitworth WC, Shah JJ, Painter JA, Mazurek GH, Maloney SA. Chuke SO, et al. Among authors: Whitworth WC. Tuberc Res Treat. 2014;2014:217969. doi: 10.1155/2014/217969. Epub 2014 Mar 6. Tuberc Res Treat. 2014. PMID: 24738031 Free PMC article.
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