Wichems CH - Search Results

1

Brain serotonin neurotransmission: an overview and update with an emphasis on serotonin subsystem heterogeneity, multiple receptors, interactions with other neurotransmitter systems, and consequent implications for understanding the actions of serotonergic drugs.

Murphy DL, Andrews AM, Wichems CH, Li Q, Tohda M, Greenberg B. Murphy DL, et al. Among authors: wichems ch. J Clin Psychiatry. 1998;59 Suppl 15:4-12. J Clin Psychiatry. 1998. PMID: 9786305 Review.

2

Molecular manipulations as tools for enhancing our understanding of 5-HT neurotransmission.

Murphy DL, Wichems C, Li Q, Heils A. Murphy DL, et al. Trends Pharmacol Sci. 1999 Jun;20(6):246-52. doi: 10.1016/s0165-6147(99)01325-5. Trends Pharmacol Sci. 1999. PMID: 10366867 Review.

3

Genetic perspectives on the serotonin transporter.

Murphy DL, Li Q, Engel S, Wichems C, Andrews A, Lesch KP, Uhl G. Murphy DL, et al. Brain Res Bull. 2001 Nov 15;56(5):487-94. doi: 10.1016/s0361-9230(01)00622-0. Brain Res Bull. 2001. PMID: 11750794 Review.

4

Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter.

Kim DK, Tolliver TJ, Huang SJ, Martin BJ, Andrews AM, Wichems C, Holmes A, Lesch KP, Murphy DL. Kim DK, et al. Neuropharmacology. 2005 Nov;49(6):798-810. doi: 10.1016/j.neuropharm.2005.08.010. Epub 2005 Sep 23. Neuropharmacology. 2005. PMID: 16183083

5

Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice.

Bengel D, Murphy DL, Andrews AM, Wichems CH, Feltner D, Heils A, Mössner R, Westphal H, Lesch KP. Bengel D, et al. Among authors: wichems ch. Mol Pharmacol. 1998 Apr;53(4):649-55. doi: 10.1124/mol.53.4.649. Mol Pharmacol. 1998. PMID: 9547354

6

Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences.

Li Q, Wichems C, Heils A, Lesch KP, Murphy DL. Li Q, et al. J Neurosci. 2000 Nov 1;20(21):7888-95. doi: 10.1523/JNEUROSCI.20-21-07888.2000. J Neurosci. 2000. PMID: 11050108 Free PMC article.

7

Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference.

Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy DL, Uhl GR. Sora I, et al. Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5300-5. doi: 10.1073/pnas.091039298. Proc Natl Acad Sci U S A. 2001. PMID: 11320258 Free PMC article.

8

Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice.

Li Q, Wichems CH, Ma L, Van de Kar LD, Garcia F, Murphy DL. Li Q, et al. Among authors: wichems ch. J Neurochem. 2003 Mar;84(6):1256-65. doi: 10.1046/j.1471-4159.2003.01607.x. J Neurochem. 2003. PMID: 12614326 Free article.

9

Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice.

Sora I, Wichems C, Takahashi N, Li XF, Zeng Z, Revay R, Lesch KP, Murphy DL, Uhl GR. Sora I, et al. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7699-704. doi: 10.1073/pnas.95.13.7699. Proc Natl Acad Sci U S A. 1998. PMID: 9636213 Free PMC article.

10

Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice.

Li Q, Wichems C, Heils A, Van De Kar LD, Lesch KP, Murphy DL. Li Q, et al. J Pharmacol Exp Ther. 1999 Dec;291(3):999-1007. J Pharmacol Exp Ther. 1999. PMID: 10565817

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