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Effects of ketamine and other rapidly acting antidepressants on hippocampal excitatory and inhibitory transmission.
Widman AJ, McMahon LL. Widman AJ, et al. Adv Pharmacol. 2020;89:3-41. doi: 10.1016/bs.apha.2020.05.001. Epub 2020 Jun 11. Adv Pharmacol. 2020. PMID: 32616211 Review.
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Zviran A, Schulman RC, Shah M, Hill STK, Deochand S, Khamnei CC, Maloney D, Patel K, Liao W, Widman AJ, Wong P, Callahan MK, Ha G, Reed S, Rotem D, Frederick D, Sharova T, Miao B, Kim T, Gydush G, Rhoades J, Huang KY, Omans ND, Bolan PO, Lipsky AH, Ang C, Malbari M, Spinelli CF, Kazancioglu S, Runnels AM, Fennessey S, Stolte C, Gaiti F, Inghirami GG, Adalsteinsson V, Houck-Loomis B, Ishii J, Wolchok JD, Boland G, Robine N, Altorki NK, Landau DA. Zviran A, et al. Among authors: widman aj. Nat Med. 2020 Jul;26(7):1114-1124. doi: 10.1038/s41591-020-0915-3. Epub 2020 Jun 1. Nat Med. 2020. PMID: 32483360
Escitalopram for agitation in Alzheimer's disease (S-CitAD): Methods and design of an investigator-initiated, randomized, controlled, multicenter clinical trial.
Ehrhardt S, Porsteinsson AP, Munro CA, Rosenberg PB, Pollock BG, Devanand DP, Mintzer J, Rajji TK, Ismail Z, Schneider LS, Baksh SN, Drye LT, Avramopoulos D, Shade DM, Lyketsos CG; S-CitAD Research Group. Ehrhardt S, et al. Alzheimers Dement. 2019 Nov;15(11):1427-1436. doi: 10.1016/j.jalz.2019.06.4946. Epub 2019 Oct 3. Alzheimers Dement. 2019. PMID: 31587995 Clinical Trial.
Rats bred for high anxiety exhibit distinct fear-related coping behavior, hippocampal physiology, and synaptic plasticity-related gene expression.
Widman AJ, Cohen JL, McCoy CR, Unroe KA, Glover ME, Khan AU, Bredemann T, McMahon LL, Clinton SM. Widman AJ, et al. Hippocampus. 2019 Oct;29(10):939-956. doi: 10.1002/hipo.23092. Epub 2019 Apr 17. Hippocampus. 2019. PMID: 30994250 Free PMC article.
Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.
Zhou D, Ota K, Nardin C, Feldman M, Widman A, Wind O, Simon A, Reilly M, Levin LR, Buck J, Wakamatsu K, Ito S, Zippin JH. Zhou D, et al. Among authors: widman a. Sci Signal. 2018 Nov 6;11(555):eaau7987. doi: 10.1126/scisignal.aau7987. Sci Signal. 2018. PMID: 30401788 Free PMC article.
Intravascular Ketamine Increases Theta-Burst but Not High Frequency Tetanus Induced LTP at CA3-CA1 Synapses Within Three Hours and Devoid of an Increase in Spine Density.
Widman AJ, Stewart AE, Erb EM, Gardner E, McMahon LL. Widman AJ, et al. Front Synaptic Neurosci. 2018 May 30;10:8. doi: 10.3389/fnsyn.2018.00008. eCollection 2018. Front Synaptic Neurosci. 2018. PMID: 29899695 Free PMC article.
Disinhibition of CA1 pyramidal cells by low-dose ketamine and other antagonists with rapid antidepressant efficacy.
Widman AJ, McMahon LL. Widman AJ, et al. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E3007-E3016. doi: 10.1073/pnas.1718883115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531088 Free PMC article.
The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial.
Scherer RW, Drye L, Mintzer J, Lanctôt K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH; ADMET 2 Research Group. Scherer RW, et al. Trials. 2018 Jan 18;19(1):46. doi: 10.1186/s13063-017-2406-5. Trials. 2018. PMID: 29347996 Free PMC article.
The genetic landscape of programmed death ligand-1 (PD-L1) alterations in head and neck cancer.
Heineman TE, Widman A, Kuan EC, St John M. Heineman TE, et al. Among authors: widman a. Laryngoscope Investig Otolaryngol. 2017 May 17;2(3):99-103. doi: 10.1002/lio2.79. eCollection 2017 Jun. Laryngoscope Investig Otolaryngol. 2017. PMID: 28894827 Free PMC article.
Precision in donor selection: Identifying ideal stem-cell donors through their T cells.
Widman A, Reshef R. Widman A, et al. Exp Hematol. 2016 Nov;44(11):1020-1023. doi: 10.1016/j.exphem.2016.07.013. Epub 2016 Aug 2. Exp Hematol. 2016. PMID: 27496363 Free PMC article. Review.
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