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Fully human anti-BAFF inhibitory monoclonal antibody tabalumab does not adversely affect T-dependent antibody responses in cynomolgus monkey (Macaca fasicularis): A summary of three pre-clinical immunotoxicology evaluations.
Komocsar WJ, Blackbourne JL, Halstead CA, Winstead CJ, Wierda D. Komocsar WJ, et al. Among authors: wierda d. J Immunotoxicol. 2016;13(1):7-19. doi: 10.3109/1547691X.2014.994793. Epub 2015 Sep 4. J Immunotoxicol. 2016. PMID: 25585959
Immunogenicity of biologically-derived therapeutics: assessment and interpretation of nonclinical safety studies.
Ponce R, Abad L, Amaravadi L, Gelzleichter T, Gore E, Green J, Gupta S, Herzyk D, Hurst C, Ivens IA, Kawabata T, Maier C, Mounho B, Rup B, Shankar G, Smith H, Thomas P, Wierda D. Ponce R, et al. Among authors: wierda d. Regul Toxicol Pharmacol. 2009 Jul;54(2):164-82. doi: 10.1016/j.yrtph.2009.03.012. Epub 2009 Apr 2. Regul Toxicol Pharmacol. 2009. PMID: 19345250
Safety evaluation of immunomodulatory biopharmaceuticals: can we improve the predictive value of preclinical studies?
Black LE, Green JD, Rener J, Dayan A, Cavagnaro JA, Spindler P, Bussiere JL, Bouchard P, Inoue T, Thomas PT, Essayan DM, Gillett NA, Hart TK, Hastings K, House RV, Latta D, Liminga U, Treacy G, Wierda D. Black LE, et al. Among authors: wierda d. Hum Exp Toxicol. 2000 Apr;19(4):205-7. doi: 10.1191/096032700678815855. Hum Exp Toxicol. 2000. PMID: 10918508 No abstract available.
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