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Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis.
Lelliott CJ, López M, Curtis RK, Parker N, Laudes M, Yeo G, Jimenez-Liñan M, Grosse J, Saha AK, Wiggins D, Hauton D, Brand MD, O'Rahilly S, Griffin JL, Gibbons GF, Vidal-Puig A. Lelliott CJ, et al. Among authors: wiggins d. FASEB J. 2005 Jul;19(9):1108-19. doi: 10.1096/fj.04-3196com. FASEB J. 2005. PMID: 15985534
Chelating agents and rat liver mitochondria.
Lund P, Wiggins D. Lund P, et al. Among authors: wiggins d. Biochim Biophys Acta. 1989 Aug 3;975(3):330-5. doi: 10.1016/s0005-2728(89)80340-8. Biochim Biophys Acta. 1989. PMID: 2503035
Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice.
Patel DD, Knight BL, Wiggins D, Humphreys SM, Gibbons GF. Patel DD, et al. Among authors: wiggins d. J Lipid Res. 2001 Mar;42(3):328-37. J Lipid Res. 2001. PMID: 11254743
The results suggest that PPAR alpha-deficiency disturbs the normal circadian regulation of certain SREBP-sensitive genes in the liver, but does not affect their response to dietary cholesterol. -- Patel, D. D., B. L. Knight, D. Wiggins, S. M. Humphreys …
The results suggest that PPAR alpha-deficiency disturbs the normal circadian regulation of certain SREBP-sensitive genes in the liver, but d …
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