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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans.
Wightman B, Ha I, Ruvkun G. Wightman B, et al. Cell. 1993 Dec 3;75(5):855-62. doi: 10.1016/0092-8674(93)90530-4. Cell. 1993. PMID: 8252622
The 20 years it took to recognize the importance of tiny RNAs.
Ruvkun G, Wightman B, Ha I. Ruvkun G, et al. Among authors: wightman b. Cell. 2004 Jan 23;116(2 Suppl):S93-6, 2 p following S96. doi: 10.1016/s0092-8674(04)00034-0. Cell. 2004. PMID: 15055593 No abstract available.
Analysis of C. elegans NR2E nuclear receptors defines three conserved clades and ligand-independent functions.
Weber KP, Alvaro CG, Baer GM, Reinert K, Cheng G, Clever S, Wightman B. Weber KP, et al. Among authors: wightman b. BMC Evol Biol. 2012 Jun 12;12:81. doi: 10.1186/1471-2148-12-81. BMC Evol Biol. 2012. PMID: 22690911 Free PMC article.
The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans.
Su CW, Tharin S, Jin Y, Wightman B, Spector M, Meili D, Tsung N, Rhiner C, Bourikas D, Stoeckli E, Garriga G, Horvitz HR, Hengartner MO. Su CW, et al. Among authors: wightman b. J Biol. 2006;5(4):9. doi: 10.1186/jbiol39. Epub 2006 May 25. J Biol. 2006. PMID: 16725058 Free PMC article.
vab-8 is a key regulator of posteriorly directed migrations in C. elegans and encodes a novel protein with kinesin motor similarity.
Wolf FW, Hung MS, Wightman B, Way J, Garriga G. Wolf FW, et al. Among authors: wightman b. Neuron. 1998 Apr;20(4):655-66. doi: 10.1016/s0896-6273(00)81006-5. Neuron. 1998. PMID: 9581759
Genes that guide growth cones along the C. elegans ventral nerve cord.
Wightman B, Baran R, Garriga G. Wightman B, et al. Development. 1997 Jul;124(13):2571-80. Development. 1997. PMID: 9216999
A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.
Ha I, Wightman B, Ruvkun G. Ha I, et al. Among authors: wightman b. Genes Dev. 1996 Dec 1;10(23):3041-50. doi: 10.1101/gad.10.23.3041. Genes Dev. 1996. PMID: 8957004
The C. elegans gene vab-8 guides posteriorly directed axon outgrowth and cell migration.
Wightman B, Clark SG, Taskar AM, Forrester WC, Maricq AV, Bargmann CI, Garriga G. Wightman B, et al. Development. 1996 Feb;122(2):671-82. Development. 1996. PMID: 8625818
Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28.
Arasu P, Wightman B, Ruvkun G. Arasu P, et al. Among authors: wightman b. Genes Dev. 1991 Oct;5(10):1825-33. doi: 10.1101/gad.5.10.1825. Genes Dev. 1991. PMID: 1916265
Dominant gain-of-function mutations that lead to misregulation of the C. elegans heterochronic gene lin-14, and the evolutionary implications of dominant mutations in pattern-formation genes.
Ruvkun G, Wightman B, B├╝rglin T, Arasu P. Ruvkun G, et al. Among authors: wightman b. Dev Suppl. 1991;1:47-54. Dev Suppl. 1991. PMID: 1742500
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