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203 results
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Recurrent DNA copy number variation in the laboratory mouse.
Egan CM, Sridhar S, Wigler M, Hall IM. Egan CM, et al. Among authors: wigler m. Nat Genet. 2007 Nov;39(11):1384-9. doi: 10.1038/ng.2007.19. Epub 2007 Oct 28. Nat Genet. 2007. PMID: 17965714
Indel variant analysis of short-read sequencing data with Scalpel.
Fang H, Bergmann EA, Arora K, Vacic V, Zody MC, Iossifov I, O'Rawe JA, Wu Y, Jimenez Barron LT, Rosenbaum J, Ronemus M, Lee YH, Wang Z, Dikoglu E, Jobanputra V, Lyon GJ, Wigler M, Schatz MC, Narzisi G. Fang H, et al. Among authors: wigler m. Nat Protoc. 2016 Dec;11(12):2529-2548. doi: 10.1038/nprot.2016.150. Epub 2016 Nov 17. Nat Protoc. 2016. PMID: 27854363 Free PMC article.
Optimizing sparse sequencing of single cells for highly multiplex copy number profiling.
Baslan T, Kendall J, Ward B, Cox H, Leotta A, Rodgers L, Riggs M, D'Italia S, Sun G, Yong M, Miskimen K, Gilmore H, Saborowski M, Dimitrova N, Krasnitz A, Harris L, Wigler M, Hicks J. Baslan T, et al. Among authors: wigler m. Genome Res. 2015 May;25(5):714-24. doi: 10.1101/gr.188060.114. Epub 2015 Apr 9. Genome Res. 2015. PMID: 25858951 Free PMC article.
Early Detection of Cancer in Blood Using Single-Cell Analysis: A Proposal.
Krasnitz A, Kendall J, Alexander J, Levy D, Wigler M. Krasnitz A, et al. Among authors: wigler m. Trends Mol Med. 2017 Jul;23(7):594-603. doi: 10.1016/j.molmed.2017.05.005. Epub 2017 Jun 3. Trends Mol Med. 2017. PMID: 28587830 Free PMC article. Review.
Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells.
Dago AE, Stepansky A, Carlsson A, Luttgen M, Kendall J, Baslan T, Kolatkar A, Wigler M, Bethel K, Gross ME, Hicks J, Kuhn P. Dago AE, et al. Among authors: wigler m. PLoS One. 2014 Aug 1;9(8):e101777. doi: 10.1371/journal.pone.0101777. eCollection 2014. PLoS One. 2014. PMID: 25084170 Free PMC article.
Reducing system noise in copy number data using principal components of self-self hybridizations.
Lee YH, Ronemus M, Kendall J, Lakshmi B, Leotta A, Levy D, Esposito D, Grubor V, Ye K, Wigler M, Yamrom B. Lee YH, et al. Among authors: wigler m. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):E103-10. doi: 10.1073/pnas.1106233109. Epub 2011 Dec 29. Proc Natl Acad Sci U S A. 2012. PMID: 22207624 Free PMC article.
Tumour evolution inferred by single-cell sequencing.
Navin N, Kendall J, Troge J, Andrews P, Rodgers L, McIndoo J, Cook K, Stepansky A, Levy D, Esposito D, Muthuswamy L, Krasnitz A, McCombie WR, Hicks J, Wigler M. Navin N, et al. Among authors: wigler m. Nature. 2011 Apr 7;472(7341):90-4. doi: 10.1038/nature09807. Epub 2011 Mar 13. Nature. 2011. PMID: 21399628 Free PMC article.
Genomic architecture characterizes tumor progression paths and fate in breast cancer patients.
Russnes HG, Vollan HKM, Lingjærde OC, Krasnitz A, Lundin P, Naume B, Sørlie T, Borgen E, Rye IH, Langerød A, Chin SF, Teschendorff AE, Stephens PJ, Månér S, Schlichting E, Baumbusch LO, Kåresen R, Stratton MP, Wigler M, Caldas C, Zetterberg A, Hicks J, Børresen-Dale AL. Russnes HG, et al. Among authors: wigler m. Sci Transl Med. 2010 Jun 30;2(38):38ra47. doi: 10.1126/scitranslmed.3000611. Sci Transl Med. 2010. PMID: 20592421 Free PMC article.
Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model.
Bric A, Miething C, Bialucha CU, Scuoppo C, Zender L, Krasnitz A, Xuan Z, Zuber J, Wigler M, Hicks J, McCombie RW, Hemann MT, Hannon GJ, Powers S, Lowe SW. Bric A, et al. Among authors: wigler m. Cancer Cell. 2009 Oct 6;16(4):324-35. doi: 10.1016/j.ccr.2009.08.015. Cancer Cell. 2009. PMID: 19800577 Free PMC article.
High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing.
Hodges E, Smith AD, Kendall J, Xuan Z, Ravi K, Rooks M, Zhang MQ, Ye K, Bhattacharjee A, Brizuela L, McCombie WR, Wigler M, Hannon GJ, Hicks JB. Hodges E, et al. Among authors: wigler m. Genome Res. 2009 Sep;19(9):1593-605. doi: 10.1101/gr.095190.109. Epub 2009 Jul 6. Genome Res. 2009. PMID: 19581485 Free PMC article.
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