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Structure and mechanism of helicases and nucleic acid translocases.
Singleton MR, Dillingham MS, Wigley DB. Singleton MR, et al. Among authors: wigley db. Annu Rev Biochem. 2007;76:23-50. doi: 10.1146/annurev.biochem.76.052305.115300. Annu Rev Biochem. 2007. PMID: 17506634 Review.
Unwinding the 'Gordian knot' of helicase action.
Soultanas P, Wigley DB. Soultanas P, et al. Among authors: wigley db. Trends Biochem Sci. 2001 Jan;26(1):47-54. doi: 10.1016/s0968-0004(00)01734-5. Trends Biochem Sci. 2001. PMID: 11165517 Review.
Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase.
Dillingham MS, Soultanas P, Wiley P, Webb MR, Wigley DB. Dillingham MS, et al. Among authors: wigley db. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8381-7. doi: 10.1073/pnas.131009598. Proc Natl Acad Sci U S A. 2001. PMID: 11459979 Free PMC article.
Structural analysis of DNA replication fork reversal by RecG.
Singleton MR, Scaife S, Wigley DB. Singleton MR, et al. Among authors: wigley db. Cell. 2001 Oct 5;107(1):79-89. doi: 10.1016/s0092-8674(01)00501-3. Cell. 2001. PMID: 11595187
Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides.
Singleton MR, Sawaya MR, Ellenberger T, Wigley DB. Singleton MR, et al. Among authors: wigley db. Cell. 2000 Jun 9;101(6):589-600. doi: 10.1016/s0092-8674(00)80871-5. Cell. 2000. PMID: 10892646
Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism.
Velankar SS, Soultanas P, Dillingham MS, Subramanya HS, Wigley DB. Velankar SS, et al. Among authors: wigley db. Cell. 1999 Apr 2;97(1):75-84. doi: 10.1016/s0092-8674(00)80716-3. Cell. 1999. PMID: 10199404
Helicases: a unifying structural theme?
Bird LE, Subramanya HS, Wigley DB. Bird LE, et al. Among authors: wigley db. Curr Opin Struct Biol. 1998 Feb;8(1):14-8. doi: 10.1016/s0959-440x(98)80004-3. Curr Opin Struct Biol. 1998. PMID: 9519291 Review.
DNA helicases: one small step for PcrA, one giant leap for RecBC?
Wigley DB. Wigley DB. Curr Biol. 2000 Jun 15;10(12):R444-6. doi: 10.1016/s0960-9822(00)00529-7. Curr Biol. 2000. PMID: 10873794 Review.
DNA helicases: 'inching forward'.
Soultanas P, Wigley DB. Soultanas P, et al. Among authors: wigley db. Curr Opin Struct Biol. 2000 Feb;10(1):124-8. doi: 10.1016/s0959-440x(99)00059-7. Curr Opin Struct Biol. 2000. PMID: 10679457 Review.
Demonstration of unidirectional single-stranded DNA translocation by PcrA helicase: measurement of step size and translocation speed.
Dillingham MS, Wigley DB, Webb MR. Dillingham MS, et al. Among authors: wigley db. Biochemistry. 2000 Jan 11;39(1):205-12. doi: 10.1021/bi992105o. Biochemistry. 2000. PMID: 10625495
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