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X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Håkansson K, Doherty AJ, Shuman S, Wigley DB. Håkansson K, et al. Among authors: wigley db. Cell. 1997 May 16;89(4):545-53. doi: 10.1016/s0092-8674(00)80236-6. Cell. 1997. PMID: 9160746
High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Juers DH, Jacobson RH, Wigley D, Zhang XJ, Huber RE, Tronrud DE, Matthews BW. Juers DH, et al. Among authors: wigley d. Protein Sci. 2000 Sep;9(9):1685-99. doi: 10.1110/ps.9.9.1685. Protein Sci. 2000. PMID: 11045615 Free PMC article.
Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase.
Dillingham MS, Soultanas P, Wiley P, Webb MR, Wigley DB. Dillingham MS, et al. Among authors: wigley db. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8381-7. doi: 10.1073/pnas.131009598. Proc Natl Acad Sci U S A. 2001. PMID: 11459979 Free PMC article.
Structural analysis of DNA replication fork reversal by RecG.
Singleton MR, Scaife S, Wigley DB. Singleton MR, et al. Among authors: wigley db. Cell. 2001 Oct 5;107(1):79-89. doi: 10.1016/s0092-8674(01)00501-3. Cell. 2001. PMID: 11595187
Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides.
Singleton MR, Sawaya MR, Ellenberger T, Wigley DB. Singleton MR, et al. Among authors: wigley db. Cell. 2000 Jun 9;101(6):589-600. doi: 10.1016/s0092-8674(00)80871-5. Cell. 2000. PMID: 10892646
Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism.
Velankar SS, Soultanas P, Dillingham MS, Subramanya HS, Wigley DB. Velankar SS, et al. Among authors: wigley db. Cell. 1999 Apr 2;97(1):75-84. doi: 10.1016/s0092-8674(00)80716-3. Cell. 1999. PMID: 10199404
Conserved themes but novel activities in recombinases and topoisomerases.
Sherratt DJ, Wigley DB. Sherratt DJ, et al. Among authors: wigley db. Cell. 1998 Apr 17;93(2):149-52. doi: 10.1016/s0092-8674(00)81566-4. Cell. 1998. PMID: 9568707 Review. No abstract available.
Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping.
Hâkansson K, Wigley DB. Hâkansson K, et al. Among authors: wigley db. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1505-10. doi: 10.1073/pnas.95.4.1505. Proc Natl Acad Sci U S A. 1998. PMID: 9465045 Free PMC article.
Helicases: a unifying structural theme?
Bird LE, Subramanya HS, Wigley DB. Bird LE, et al. Among authors: wigley db. Curr Opin Struct Biol. 1998 Feb;8(1):14-8. doi: 10.1016/s0959-440x(98)80004-3. Curr Opin Struct Biol. 1998. PMID: 9519291 Review.
Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.
Soultanas P, Dillingham MS, Wiley P, Webb MR, Wigley DB. Soultanas P, et al. Among authors: wigley db. EMBO J. 2000 Jul 17;19(14):3799-810. doi: 10.1093/emboj/19.14.3799. EMBO J. 2000. PMID: 10899133 Free PMC article.
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