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A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV. Spasov AA, et al. Among authors: wikman gk. Phytomedicine. 2000 Apr;7(2):85-9. doi: 10.1016/S0944-7113(00)80078-1. Phytomedicine. 2000. PMID: 10839209 Clinical Trial.
Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data.
Panossian A, Hamm R, Wikman G, Efferth T. Panossian A, et al. Phytomedicine. 2014 Sep 25;21(11):1325-48. doi: 10.1016/j.phymed.2014.07.008. Epub 2014 Aug 7. Phytomedicine. 2014. PMID: 25172797
Adaptogens exert a stress-protective effect by modulation of expression of molecular chaperones.
Panossian A, Wikman G, Kaur P, Asea A. Panossian A, et al. Phytomedicine. 2009 Jun;16(6-7):617-22. doi: 10.1016/j.phymed.2008.12.003. Epub 2009 Feb 1. Phytomedicine. 2009. PMID: 19188053
Pharmacokinetic and pharmacodynamic study of interaction of Rhodiola rosea SHR-5 extract with warfarin and theophylline in rats.
Panossian A, Hovhannisyan A, Abrahamyan H, Gabrielyan E, Wikman G. Panossian A, et al. Phytother Res. 2009 Mar;23(3):351-7. doi: 10.1002/ptr.2631. Phytother Res. 2009. PMID: 18844284
The influence of adaptogens on ultraweak biophoton emission: a pilot-experiment.
Schutgens FW, Neogi P, van Wijk EP, van Wijk R, Wikman G, Wiegant FA. Schutgens FW, et al. Phytother Res. 2009 Aug;23(8):1103-8. doi: 10.1002/ptr.2753. Phytother Res. 2009. PMID: 19170145 Clinical Trial.
A phase I clinical study of Andrographis paniculata fixed combination Kan Jang versus ginseng and valerian on the semen quality of healthy male subjects.
Mkrtchyan A, Panosyan V, Panossian A, Wikman G, Wagner H. Mkrtchyan A, et al. Phytomedicine. 2005 Jun;12(6-7):403-9. doi: 10.1016/j.phymed.2004.10.004. Phytomedicine. 2005. PMID: 16008115 Clinical Trial.
Impact of Chisan (ADAPT-232) on the quality-of-life and its efficacy as an adjuvant in the treatment of acute non-specific pneumonia.
Narimanian M, Badalyan M, Panosyan V, Gabrielyan E, Panossian A, Wikman G, Wagner H. Narimanian M, et al. Phytomedicine. 2005 Nov;12(10):723-9. doi: 10.1016/j.phymed.2004.11.004. Phytomedicine. 2005. PMID: 16323290 Clinical Trial.
Randomized trial of a fixed combination (KanJang) of herbal extracts containing Adhatoda vasica, Echinacea purpurea and Eleutherococcus senticosus in patients with upper respiratory tract infections.
Narimanian M, Badalyan M, Panosyan V, Gabrielyan E, Panossian A, Wikman G, Wagner H. Narimanian M, et al. Phytomedicine. 2005 Aug;12(8):539-47. doi: 10.1016/j.phymed.2004.10.001. Phytomedicine. 2005. PMID: 16121513 Clinical Trial.
Double-blind, placebo-controlled, randomized, pilot clinical trial of ImmunoGuard--a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. and Glycyrrhiza glabra L. extracts in patients with Familial Mediterranean Fever.
Amaryan G, Astvatsatryan V, Gabrielyan E, Panossian A, Panosyan V, Wikman G. Amaryan G, et al. Phytomedicine. 2003 May;10(4):271-85. doi: 10.1078/094471103322004767. Phytomedicine. 2003. PMID: 12809357 Clinical Trial.
A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work.
Shevtsov VA, Zholus BI, Shervarly VI, Vol'skij VB, Korovin YP, Khristich MP, Roslyakova NA, Wikman G. Shevtsov VA, et al. Phytomedicine. 2003 Mar;10(2-3):95-105. doi: 10.1078/094471103321659780. Phytomedicine. 2003. PMID: 12725561 Clinical Trial.
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