Poisson regression analysis demonstrated that older individuals received aldosterone antagonists less frequently (Prevalence Ratio (PR): 0.64, 95%CI 0.54; 0.77, p < 0.0001). This effect persisted after additional adjustment for kidney function (PR: 0.53, 95%CI 0.44; 0.6
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Table representation of search results timeline featuring number of search results per year.
| Year | Number of Results |
|---|---|
| 2002 | 2 |
| 2004 | 1 |
| 2006 | 1 |
| 2007 | 2 |
| 2008 | 3 |
| 2009 | 7 |
| 2010 | 10 |
| 2011 | 18 |
| 2012 | 20 |
| 2013 | 32 |
| 2014 | 19 |
| 2015 | 32 |
| 2016 | 23 |
| 2017 | 29 |
| 2018 | 33 |
| 2019 | 44 |
| 2020 | 45 |
| 2021 | 56 |
| 2022 | 39 |
| 2023 | 43 |
| 2024 | 36 |
| 2025 | 42 |
| 2026 | 20 |
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HF was associated with an increase of epigenetic age by on average 19.0 [11.0; 29.0] years and with a global decrease in methylation across all phenotypes (Odds ratio [OR]: 1.33 [95% CI: 1.17-1.51], p < 0.0001). Epigenetic clocks strongly predicted incident worsening of
…RESULTS: Hearing loss (HL 20 dB; both ears) revealed a significant negative association with planning ability total score (beta = -0.346, p < 0.01), but not significantly with clinical executive dysfunction (<16. Percentile total TOL) (OR=1.109, p = 0.43). H
…In Cox regression analysis, CI independently predicted all-cause death [hazard ratio (HR) per standard deviation (SD) decrease in pHRR (HRSD) 1.77 (1.42; 2.21); P < .0001], cardiac death [HRSD 1.74 (1.08; 2.80); P = .023], and worsening of HF (HRSD 1.39 [1.01; 1.
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