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An Evolutionary Trace method defines functionally important bases and sites common to RNA families.

Novikov IB, Wilkins AD, Lichtarge O. Novikov IB, et al. Among authors: wilkins ad. PLoS Comput Biol. 2020 Mar 24;16(3):e1007583. doi: 10.1371/journal.pcbi.1007583. eCollection 2020 Mar. PLoS Comput Biol. 2020. PMID: 32208421 Free PMC article.

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Evolution: a guide to perturb protein function and networks.

Lichtarge O, Wilkins A. Lichtarge O, et al. Curr Opin Struct Biol. 2010 Jun;20(3):351-9. doi: 10.1016/j.sbi.2010.04.002. Epub 2010 May 3. Curr Opin Struct Biol. 2010. PMID: 20444593 Free PMC article. Review.

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Sequence and structure continuity of evolutionary importance improves protein functional site discovery and annotation.

Wilkins AD, Lua R, Erdin S, Ward RM, Lichtarge O. Wilkins AD, et al. Protein Sci. 2010 Jul;19(7):1296-311. doi: 10.1002/pro.406. Protein Sci. 2010. PMID: 20506260 Free PMC article.

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Evolutionary trace for prediction and redesign of protein functional sites.

Wilkins A, Erdin S, Lua R, Lichtarge O. Wilkins A, et al. Methods Mol Biol. 2012;819:29-42. doi: 10.1007/978-1-61779-465-0_3. Methods Mol Biol. 2012. PMID: 22183528 Free PMC article.

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The use of evolutionary patterns in protein annotation.

Wilkins AD, Bachman BJ, Erdin S, Lichtarge O. Wilkins AD, et al. Curr Opin Struct Biol. 2012 Jun;22(3):316-25. doi: 10.1016/j.sbi.2012.05.001. Epub 2012 May 24. Curr Opin Struct Biol. 2012. PMID: 22633559 Free PMC article. Review.

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Identification of a candidate therapeutic autophagy-inducing peptide.

Shoji-Kawata S, Sumpter R, Leveno M, Campbell GR, Zou Z, Kinch L, Wilkins AD, Sun Q, Pallauf K, MacDuff D, Huerta C, Virgin HW, Helms JB, Eerland R, Tooze SA, Xavier R, Lenschow DJ, Yamamoto A, King D, Lichtarge O, Grishin NV, Spector SA, Kaloyanova DV, Levine B. Shoji-Kawata S, et al. Among authors: wilkins ad. Nature. 2013 Feb 14;494(7436):201-6. doi: 10.1038/nature11866. Epub 2013 Jan 30. Nature. 2013. PMID: 23364696 Free PMC article.

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An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders.

Baker SA, Chen L, Wilkins AD, Yu P, Lichtarge O, Zoghbi HY. Baker SA, et al. Among authors: wilkins ad. Cell. 2013 Feb 28;152(5):984-96. doi: 10.1016/j.cell.2013.01.038. Cell. 2013. PMID: 23452848 Free PMC article.

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Accounting for epistatic interactions improves the functional analysis of protein structures.

Wilkins AD, Venner E, Marciano DC, Erdin S, Atri B, Lua RC, Lichtarge O. Wilkins AD, et al. Bioinformatics. 2013 Nov 1;29(21):2714-21. doi: 10.1093/bioinformatics/btt489. Epub 2013 Sep 10. Bioinformatics. 2013. PMID: 24021383 Free PMC article.

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Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases.

Young E, Zheng ZY, Wilkins AD, Jeong HT, Li M, Lichtarge O, Chang EC. Young E, et al. Among authors: wilkins ad. Mol Cell Biol. 2014 Feb;34(3):374-85. doi: 10.1128/MCB.01248-13. Epub 2013 Nov 18. Mol Cell Biol. 2014. PMID: 24248599 Free PMC article.

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Prediction and redesign of protein-protein interactions.

Lua RC, Marciano DC, Katsonis P, Adikesavan AK, Wilkins AD, Lichtarge O. Lua RC, et al. Among authors: wilkins ad. Prog Biophys Mol Biol. 2014 Nov-Dec;116(2-3):194-202. doi: 10.1016/j.pbiomolbio.2014.05.004. Epub 2014 May 27. Prog Biophys Mol Biol. 2014. PMID: 24878423 Free PMC article. Review.

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