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The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.
Hung LW, Villemagne VL, Cheng L, Sherratt NA, Ayton S, White AR, Crouch PJ, Lim S, Leong SL, Wilkins S, George J, Roberts BR, Pham CL, Liu X, Chiu FC, Shackleford DM, Powell AK, Masters CL, Bush AI, O'Keefe G, Culvenor JG, Cappai R, Cherny RA, Donnelly PS, Hill AF, Finkelstein DI, Barnham KJ. Hung LW, et al. Among authors: wilkins s. J Exp Med. 2012 Apr 9;209(4):837-54. doi: 10.1084/jem.20112285. Epub 2012 Apr 2. J Exp Med. 2012. PMID: 22473957 Free PMC article.
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta.
Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, Deleva K, Lynch T, Kok G, Ritchie CW, Tanzi RE, Cappai R, Masters CL, Barnham KJ, Bush AI. Adlard PA, et al. Among authors: wilkins s. Neuron. 2008 Jul 10;59(1):43-55. doi: 10.1016/j.neuron.2008.06.018. Neuron. 2008. PMID: 18614028 Free article.
Targeting the progression of Parkinson's disease.
George JL, Mok S, Moses D, Wilkins S, Bush AI, Cherny RA, Finkelstein DI. George JL, et al. Among authors: wilkins s. Curr Neuropharmacol. 2009 Mar;7(1):9-36. doi: 10.2174/157015909787602814. Curr Neuropharmacol. 2009. PMID: 19721815 Free PMC article.
The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease.
Finkelstein DI, Billings JL, Adlard PA, Ayton S, Sedjahtera A, Masters CL, Wilkins S, Shackleford DM, Charman SA, Bal W, Zawisza IA, Kurowska E, Gundlach AL, Ma S, Bush AI, Hare DJ, Doble PA, Crawford S, Gautier EC, Parsons J, Huggins P, Barnham KJ, Cherny RA. Finkelstein DI, et al. Among authors: wilkins s. Acta Neuropathol Commun. 2017 Jun 28;5(1):53. doi: 10.1186/s40478-017-0456-2. Acta Neuropathol Commun. 2017. PMID: 28659169 Free PMC article.
Correction to: The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease.
Finkelstein DI, Billings JL, Adlard PA, Ayton S, Sedjahtera A, Masters CL, Wilkins S, Shackleford DM, Charman SA, Bal W, Zawisza IA, Kurowska E, Gundlach AL, Ma S, Bush AI, Hare DJ, Doble PA, Crawford S, Gautier ECL, Parsons J, Huggins P, Barnham KJ, Cherny RA. Finkelstein DI, et al. Among authors: wilkins s. Acta Neuropathol Commun. 2021 Sep 29;9(1):161. doi: 10.1186/s40478-021-01258-8. Acta Neuropathol Commun. 2021. PMID: 34588001 Free PMC article. No abstract available.
457 results