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237 results
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The erythromycin breath test reflects P-glycoprotein function independently of cytochrome P450 3A activity.
Kurnik D, Wood AJ, Wilkinson GR. Kurnik D, et al. Among authors: wilkinson gr. Clin Pharmacol Ther. 2006 Sep;80(3):228-34. doi: 10.1016/j.clpt.2006.06.002. Clin Pharmacol Ther. 2006. PMID: 16952489 Clinical Trial.
Commentary: a physiological approach to hepatic drug clearance.
Wilkinson GR, Shand DG. Wilkinson GR, et al. Clin Pharmacol Ther. 1975 Oct;18(4):377-90. doi: 10.1002/cpt1975184377. Clin Pharmacol Ther. 1975. PMID: 1164821
Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.
Thummel KE, O'Shea D, Paine MF, Shen DD, Kunze KL, Perkins JD, Wilkinson GR. Thummel KE, et al. Among authors: wilkinson gr. Clin Pharmacol Ther. 1996 May;59(5):491-502. doi: 10.1016/S0009-9236(96)90177-0. Clin Pharmacol Ther. 1996. PMID: 8646820 Clinical Trial.
Effects of route of administration and blood flow on hepatic drug elimination.
Shand DG, Kornhauser DM, Wilkinson GR. Shand DG, et al. Among authors: wilkinson gr. J Pharmacol Exp Ther. 1975 Dec;195(3):424-32. J Pharmacol Exp Ther. 1975. PMID: 1195129
The effect of cirrhosis on the disposition and elimination of meperidine in man.
Klotz U, McHorse TS, Wilkinson GR, Schenker S. Klotz U, et al. Among authors: wilkinson gr. Clin Pharmacol Ther. 1974 Oct;16(4):667-75. doi: 10.1002/cpt1974164667. Clin Pharmacol Ther. 1974. PMID: 4419525 No abstract available.
CYP3A activity in European American and Japanese men using midazolam as an in vivo probe.
Tateishi T, Watanabe M, Nakura H, Asoh M, Shirai H, Mizorogi Y, Kobayashi S, Thummel KE, Wilkinson GR. Tateishi T, et al. Among authors: wilkinson gr. Clin Pharmacol Ther. 2001 May;69(5):333-9. doi: 10.1067/mcp.2001.115447. Clin Pharmacol Ther. 2001. PMID: 11372001 Clinical Trial.
Meperidine disposition in man: influence of urinary pH and route of administration.
Verbeeck RK, Branch RA, Wilkinson GR. Verbeeck RK, et al. Among authors: wilkinson gr. Clin Pharmacol Ther. 1981 Nov;30(5):619-28. doi: 10.1038/clpt.1981.213. Clin Pharmacol Ther. 1981. PMID: 7297021
Disposition of furosemide in functionally hepatectomized dogs.
Verbeeck RK, Gerkens JF, Wilkinson GR, Branch RA. Verbeeck RK, et al. Among authors: wilkinson gr. J Pharmacol Exp Ther. 1981 Mar;216(3):479-83. J Pharmacol Exp Ther. 1981. PMID: 7205627
Furosemide disposition in cirrhosis.
Verbeeck RK, Patwardhan RV, Villeneuve JP, Wilkinson GR, Branch RA. Verbeeck RK, et al. Among authors: wilkinson gr. Clin Pharmacol Ther. 1982 Jun;31(6):719-25. doi: 10.1038/clpt.1982.101. Clin Pharmacol Ther. 1982. PMID: 7075120
Effect of thyrotoxicosis on liver blood flow and propranolol disposition after long-term dosing.
Wells PG, Feely J, Wilkinson GR, Wood AJ. Wells PG, et al. Among authors: wilkinson gr. Clin Pharmacol Ther. 1983 May;33(5):603-8. doi: 10.1038/clpt.1983.81. Clin Pharmacol Ther. 1983. PMID: 6839632
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