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Muscarinic M3 receptor coupling and regulation.
Nahorski SR, Tobin AB, Willars GB. Nahorski SR, et al. Life Sci. 1997;60(13-14):1039-45. doi: 10.1016/s0024-3205(97)00045-3. Life Sci. 1997. PMID: 9121345 Review.
Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor.
Alhosaini K, Bahattab O, Qassam H, Challiss RAJ, Willars GB. Alhosaini K, et al. Among authors: willars gb. Mol Pharmacol. 2018 Jul;94(1):674-688. doi: 10.1124/mol.117.111070. Epub 2018 May 3. Mol Pharmacol. 2018. PMID: 29724789
Paradoxical behavior of neuromedin U in isolated smooth muscle cells and intact tissue.
Brighton PJ, Wise A, Dass NB, Willars GB. Brighton PJ, et al. J Pharmacol Exp Ther. 2008 Apr;325(1):154-64. doi: 10.1124/jpet.107.132803. Epub 2008 Jan 7. J Pharmacol Exp Ther. 2008. PMID: 18180374
cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.
Xie J, Ponuwei GA, Moore CE, Willars GB, Tee AR, Herbert TP. Xie J, et al. Cell Signal. 2011 Dec;23(12):1927-35. doi: 10.1016/j.cellsig.2011.06.025. Epub 2011 Jul 6. Cell Signal. 2011. PMID: 21763421 Free PMC article.
Comparative effects of the endogenous agonist glucagon-like peptide-1 (GLP-1)-(7-36) amide and the small-molecule ago-allosteric agent "compound 2" at the GLP-1 receptor.
Coopman K, Huang Y, Johnston N, Bradley SJ, Wilkinson GF, Willars GB. Coopman K, et al. J Pharmacol Exp Ther. 2010 Sep 1;334(3):795-808. doi: 10.1124/jpet.110.166009. Epub 2010 May 27. J Pharmacol Exp Ther. 2010. PMID: 20507928 Free PMC article.
Full and partial agonists of muscarinic M3 receptors reveal single and oscillatory Ca2+ responses by beta 2-adrenoceptors.
Kurian N, Hall CJ, Wilkinson GF, Sullivan M, Tobin AB, Willars GB. Kurian N, et al. J Pharmacol Exp Ther. 2009 Aug;330(2):502-12. doi: 10.1124/jpet.109.153619. Epub 2009 May 6. J Pharmacol Exp Ther. 2009. PMID: 19420300 Free PMC article.
Lack of receptor-selective effects of either RGS2, RGS3 or RGS4 on muscarinic M3- and gonadotropin-releasing hormone receptor-mediated signalling through G alpha q/11.
Karakoula A, Tovey SC, Brighton PJ, Willars GB. Karakoula A, et al. Eur J Pharmacol. 2008 Jun 10;587(1-3):16-24. doi: 10.1016/j.ejphar.2008.03.047. Epub 2008 Apr 4. Eur J Pharmacol. 2008. PMID: 18457830
Mammalian RGS proteins: multifunctional regulators of cellular signalling.
Willars GB. Willars GB. Semin Cell Dev Biol. 2006 Jun;17(3):363-76. doi: 10.1016/j.semcdb.2006.03.005. Epub 2006 Apr 3. Semin Cell Dev Biol. 2006. PMID: 16687250 Review.
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