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Microtubule dynamics during the cell cycle: the effects of taxol and nocodazole on the microtubule system of Pt K2 cells at different stages of the mitotic cycle.
De Brabander M, Geuens G, Nuydens R, Willebrords R, Aerts F, De Mey J. De Brabander M, et al. Among authors: willebrords r. Int Rev Cytol. 1986;101:215-74. doi: 10.1016/s0074-7696(08)60250-8. Int Rev Cytol. 1986. PMID: 2870994 No abstract available.
Microtubule dynamics and the mitotic cycle: a model.
De Brabander M, Aerts F, De Mey J, Geuens G, Moeremans M, Nuydens R, Willebrords R. De Brabander M, et al. Among authors: willebrords r. Basic Life Sci. 1985;36:269-78. doi: 10.1007/978-1-4613-2127-9_17. Basic Life Sci. 1985. PMID: 3913416 No abstract available.
Microtubule assembly in living cells after release from nocodazole block: the effects of metabolic inhibitors, taxol and PH.
De Brabander M, Geuens G, Nuydens R, Willebrords R, De Mey J. De Brabander M, et al. Among authors: willebrords r. Cell Biol Int Rep. 1981 Sep;5(9):913-20. doi: 10.1016/0309-1651(81)90206-x. Cell Biol Int Rep. 1981. PMID: 6117376 No abstract available.
Microtubule stability and assembly in living cells: the influence of metabolic inhibitors, taxol and pH.
De Brabander M, Geuens G, Nuydens R, Willebrords R, De Mey J. De Brabander M, et al. Among authors: willebrords r. Cold Spring Harb Symp Quant Biol. 1982;46 Pt 1:227-40. doi: 10.1101/sqb.1982.046.01.026. Cold Spring Harb Symp Quant Biol. 1982. PMID: 6125293 No abstract available.
Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores.
De Brabander M, Geuens G, Nuydens R, Willebrords R, De Mey J. De Brabander M, et al. Among authors: willebrords r. Proc Natl Acad Sci U S A. 1981 Sep;78(9):5608-612. doi: 10.1073/pnas.78.9.5608. Proc Natl Acad Sci U S A. 1981. PMID: 6117858 Free PMC article.
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein.
Roymans D, De Bondt HL, Arnoult E, Geluykens P, Gevers T, Van Ginderen M, Verheyen N, Kim H, Willebrords R, Bonfanti JF, Bruinzeel W, Cummings MD, van Vlijmen H, Andries K. Roymans D, et al. Among authors: willebrords r. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):308-13. doi: 10.1073/pnas.0910108106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2010. PMID: 19966279 Free PMC article.
Tubulozole: a new stereoselective microtubule inhibitor.
De Brabander M, Geuens G, Nuydens R, Willebrords R, Moeremans M, Van Ginckel R, Distelmans W, Dragonetti C, Mareel M. De Brabander M, et al. Among authors: willebrords r. Ann N Y Acad Sci. 1986;466:757-66. doi: 10.1111/j.1749-6632.1986.tb38457.x. Ann N Y Acad Sci. 1986. PMID: 3460448 No abstract available.
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121).
Bonfanti JF, Meyer C, Doublet F, Fortin J, Muller P, Queguiner L, Gevers T, Janssens P, Szel H, Willebrords R, Timmerman P, Wuyts K, van Remoortere P, Janssens F, Wigerinck P, Andries K. Bonfanti JF, et al. Among authors: willebrords r. J Med Chem. 2008 Feb 28;51(4):875-96. doi: 10.1021/jm701284j. Epub 2008 Feb 7. J Med Chem. 2008. PMID: 18254606
Substituted benzimidazoles with nanomolar activity against respiratory syncytial virus.
Andries K, Moeremans M, Gevers T, Willebrords R, Sommen C, Lacrampe J, Janssens F, Wyde PR. Andries K, et al. Among authors: willebrords r. Antiviral Res. 2003 Nov;60(3):209-19. doi: 10.1016/j.antiviral.2003.07.004. Antiviral Res. 2003. PMID: 14638397
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure-property relationship.
Bonfanti JF, Doublet F, Fortin J, Lacrampe J, Guillemont J, Muller P, Queguiner L, Arnoult E, Gevers T, Janssens P, Szel H, Willebrords R, Timmerman P, Wuyts K, Janssens F, Sommen C, Wigerinck P, Andries K. Bonfanti JF, et al. Among authors: willebrords r. J Med Chem. 2007 Sep 20;50(19):4572-84. doi: 10.1021/jm070143x. Epub 2007 Aug 28. J Med Chem. 2007. PMID: 17722899
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