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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.
Morgenbesser SD, Williams BO, Jacks T, DePinho RA. Morgenbesser SD, et al. Nature. 1994 Sep 1;371(6492):72-4. doi: 10.1038/371072a0. Nature. 1994. PMID: 8072529
Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice.
Yamasaki L, Bronson R, Williams BO, Dyson NJ, Harlow E, Jacks T. Yamasaki L, et al. Nat Genet. 1998 Apr;18(4):360-4. doi: 10.1038/ng0498-360. Nat Genet. 1998. PMID: 9537419
Cooperative tumorigenic effects of germline mutations in Rb and p53.
Williams BO, Remington L, Albert DM, Mukai S, Bronson RT, Jacks T. Williams BO, et al. Nat Genet. 1994 Aug;7(4):480-4. doi: 10.1038/ng0894-480. Nat Genet. 1994. PMID: 7951317
A subset of p53-deficient embryos exhibit exencephaly.
Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T. Sah VP, et al. Nat Genet. 1995 Jun;10(2):175-80. doi: 10.1038/ng0695-175. Nat Genet. 1995. PMID: 7663512
Tumorigenic and developmental effects of combined germ-line mutations in Rb and p53.
Williams BO, Morgenbesser SD, DePinho RA, Jacks T. Williams BO, et al. Cold Spring Harb Symp Quant Biol. 1994;59:449-57. doi: 10.1101/sqb.1994.059.01.050. Cold Spring Harb Symp Quant Biol. 1994. PMID: 7587099 No abstract available.
Targeted disruption of p107: functional overlap between p107 and Rb.
Lee MH, Williams BO, Mulligan G, Mukai S, Bronson RT, Dyson N, Harlow E, Jacks T. Lee MH, et al. Genes Dev. 1996 Jul 1;10(13):1621-32. doi: 10.1101/gad.10.13.1621. Genes Dev. 1996. PMID: 8682293
The Rb tumor suppressor is required for stress erythropoiesis.
Spike BT, Dirlam A, Dibling BC, Marvin J, Williams BO, Jacks T, Macleod KF. Spike BT, et al. EMBO J. 2004 Oct 27;23(21):4319-29. doi: 10.1038/sj.emboj.7600432. Epub 2004 Sep 30. EMBO J. 2004. PMID: 15457215 Free PMC article.
Tumor spectrum analysis in p53-mutant mice.
Jacks T, Remington L, Williams BO, Schmitt EM, Halachmi S, Bronson RT, Weinberg RA. Jacks T, et al. Curr Biol. 1994 Jan 1;4(1):1-7. doi: 10.1016/s0960-9822(00)00002-6. Curr Biol. 1994. PMID: 7922305
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