Williams DK - Search Results

1

Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics.

Gurley BJ, Swain A, Williams DK, Barone G, Battu SK. Gurley BJ, et al. Among authors: williams dk. Mol Nutr Food Res. 2008 Jul;52(7):772-9. doi: 10.1002/mnfr.200700081. Mol Nutr Food Res. 2008. PMID: 18214850 Free PMC article.

2

Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans.

Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry WB, Cui Y, Ang CY. Gurley BJ, et al. Among authors: williams dk. Clin Pharmacol Ther. 2002 Sep;72(3):276-87. doi: 10.1067/mcp.2002.126913. Clin Pharmacol Ther. 2002. PMID: 12235448 Clinical Trial.

3

Influence of grapefruit juice on the systemic availability of itraconazole oral solution in healthy adult volunteers.

Gubbins PO, McConnell SA, Gurley BJ, Fincher TK, Franks AM, Williams DK, Penzak SR, Saccente M. Gubbins PO, et al. Among authors: williams dk. Pharmacotherapy. 2004 Apr;24(4):460-7. doi: 10.1592/phco.24.5.460.33350. Pharmacotherapy. 2004. PMID: 15098799 Clinical Trial.

4

In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto.

Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry WB, Carrier J, Khan IA, Edwards DJ, Shah A. Gurley BJ, et al. Among authors: williams dk. Clin Pharmacol Ther. 2004 Nov;76(5):428-40. doi: 10.1016/j.clpt.2004.07.007. Clin Pharmacol Ther. 2004. PMID: 15536458 Clinical Trial.

5

In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes.

Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry WB, Khan IA, Shah A. Gurley BJ, et al. Among authors: williams dk. Clin Pharmacol Ther. 2005 May;77(5):415-26. doi: 10.1016/j.clpt.2005.01.009. Clin Pharmacol Ther. 2005. PMID: 15900287 Free PMC article. Clinical Trial.

6

Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba.

Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry WB, Cui Y, Ang CY. Gurley BJ, et al. Among authors: williams dk. Drugs Aging. 2005;22(6):525-39. doi: 10.2165/00002512-200522060-00006. Drugs Aging. 2005. PMID: 15974642 Free PMC article. Clinical Trial.

7

Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans.

Gurley BJ, Barone GW, Williams DK, Carrier J, Breen P, Yates CR, Song PF, Hubbard MA, Tong Y, Cheboyina S. Gurley BJ, et al. Among authors: williams dk. Drug Metab Dispos. 2006 Jan;34(1):69-74. doi: 10.1124/dmd.105.006312. Epub 2005 Oct 12. Drug Metab Dispos. 2006. PMID: 16221754 Free PMC article. Clinical Trial.

8

Assessing the clinical significance of botanical supplementation on human cytochrome P450 3A activity: comparison of a milk thistle and black cohosh product to rifampin and clarithromycin.

Gurley B, Hubbard MA, Williams DK, Thaden J, Tong Y, Gentry WB, Breen P, Carrier DJ, Cheboyina S. Gurley B, et al. Among authors: williams dk. J Clin Pharmacol. 2006 Feb;46(2):201-13. doi: 10.1177/0091270005284854. J Clin Pharmacol. 2006. PMID: 16432272 Free PMC article. Clinical Trial.

9

Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans.

Gurley BJ, Swain A, Barone GW, Williams DK, Breen P, Yates CR, Stuart LB, Hubbard MA, Tong Y, Cheboyina S. Gurley BJ, et al. Among authors: williams dk. Drug Metab Dispos. 2007 Feb;35(2):240-5. doi: 10.1124/dmd.106.012708. Epub 2006 Nov 1. Drug Metab Dispos. 2007. PMID: 17079360 Free PMC article. Clinical Trial.

10

Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo.

Gurley BJ, Swain A, Hubbard MA, Hartsfield F, Thaden J, Williams DK, Gentry WB, Tong Y. Gurley BJ, et al. Among authors: williams dk. Clin Pharmacol Ther. 2008 Jan;83(1):61-9. doi: 10.1038/sj.clpt.6100222. Epub 2007 May 9. Clin Pharmacol Ther. 2008. PMID: 17495878 Clinical Trial.

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