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154 results

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Page 1
Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors.
Williams KB, Larsson AT, Keller BJ, Chaney KE, Williams RL, Bhunia MM, Draper GM, Jubenville TA, Hudson WA, Georg GI, Moertel CL, Ratner N, Largaespada DA. Williams KB, et al. Mol Cancer Ther. 2025 Oct 2:10.1158/1535-7163.MCT-24-1053. doi: 10.1158/1535-7163.MCT-24-1053. Online ahead of print. Mol Cancer Ther. 2025. PMID: 41036607 Free PMC article.
Techniques for Validating CRISPR Changes Using RNA-Sequencing Data.
Rathe SK, Marko TA, Edwards EN, Ridder PH, Varshney J, Williams KB, Johnson JE, Moriarity BS, Largaespada DA. Rathe SK, et al. Among authors: williams kb. Genes (Basel). 2025 Mar 24;16(4):369. doi: 10.3390/genes16040369. Genes (Basel). 2025. PMID: 40282329 Free PMC article.
Multiomic analyses reveal new targets of polycomb repressor complex 2 in Schwann lineage cells and malignant peripheral nerve sheath tumors.
Bhunia MM, Stehn CM, Jubenville TA, Novacek EL, Larsson AT, Madala M, Suppiah S, Velez-Reyes GL, Williams KB, Sokolowski M, Williams RL, Finnerty SJ, Temiz NA, Caride A, Bhagwate AV, Nagaraj NK, Lee JH, Ordog T, Zadeh G, Largaespada DA. Bhunia MM, et al. Among authors: williams kb. Neurooncol Adv. 2024 Nov 9;6(1):vdae188. doi: 10.1093/noajnl/vdae188. eCollection 2024 Jan-Dec. Neurooncol Adv. 2024. PMID: 39620202 Free PMC article.
Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors.
Williams KB, Larsson AT, Keller BJ, Chaney KE, Williams RL, Bhunia MM, Draper GM, Jubenville TA, Hudson WA, Moertel CL, Ratner N, Largaespada DA. Williams KB, et al. bioRxiv [Preprint]. 2024 Nov 1:2024.03.25.585959. doi: 10.1101/2024.03.25.585959. bioRxiv. 2024. Update in: Mol Cancer Ther. 2025 Oct 2. doi: 10.1158/1535-7163.MCT-24-1053. PMID: 38585724 Free PMC article. Updated. Preprint.
Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology.
Larsson AT, Bhatia H, Calizo A, Pollard K, Zhang X, Conniff E, Tibbitts JF, Rono E, Cummins K, Osum SH, Williams KB, Crampton AL, Jubenville T, Schefer D, Yang K, Lyu Y, Pino JC, Bade J, Gross JM, Lisok A, Dehner CA, Chrisinger JSA, He K, Gosline SJC, Pratilas CA, Largaespada DA, Wood DK, Hirbe AC. Larsson AT, et al. Among authors: williams kb. Neuro Oncol. 2023 Nov 2;25(11):2044-2057. doi: 10.1093/neuonc/noad097. Neuro Oncol. 2023. PMID: 37246765 Free PMC article.
154 results