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Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.
Krylova IN, Sablin EP, Moore J, Xu RX, Waitt GM, MacKay JA, Juzumiene D, Bynum JM, Madauss K, Montana V, Lebedeva L, Suzawa M, Williams JD, Williams SP, Guy RK, Thornton JW, Fletterick RJ, Willson TM, Ingraham HA. Krylova IN, et al. Among authors: willson tm. Cell. 2005 Feb 11;120(3):343-55. doi: 10.1016/j.cell.2005.01.024. Cell. 2005. PMID: 15707893
Progress towards a public chemogenomic set for protein kinases and a call for contributions.
Drewry DH, Wells CI, Andrews DM, Angell R, Al-Ali H, Axtman AD, Capuzzi SJ, Elkins JM, Ettmayer P, Frederiksen M, Gileadi O, Gray N, Hooper A, Knapp S, Laufer S, Luecking U, Michaelides M, Müller S, Muratov E, Denny RA, Saikatendu KS, Treiber DK, Zuercher WJ, Willson TM. Drewry DH, et al. Among authors: willson tm. PLoS One. 2017 Aug 2;12(8):e0181585. doi: 10.1371/journal.pone.0181585. eCollection 2017. PLoS One. 2017. PMID: 28767711 Free PMC article.
Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma.
Agostini M, Gurnell M, Savage DB, Wood EM, Smith AG, Rajanayagam O, Garnes KT, Levinson SH, Xu HE, Schwabe JW, Willson TM, O'Rahilly S, Chatterjee VK. Agostini M, et al. Among authors: willson tm. Endocrinology. 2004 Apr;145(4):1527-38. doi: 10.1210/en.2003-1271. Epub 2003 Dec 4. Endocrinology. 2004. PMID: 14657011
Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages.
Whitney KD, Watson MA, Goodwin B, Galardi CM, Maglich JM, Wilson JG, Willson TM, Collins JL, Kliewer SA. Whitney KD, et al. Among authors: willson tm. J Biol Chem. 2001 Nov 23;276(47):43509-15. doi: 10.1074/jbc.M106155200. Epub 2001 Aug 23. J Biol Chem. 2001. PMID: 11546778
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