Willson TM - Search Results

1

Genomics versus orphan nuclear receptors--a half-time report.

Willson TM, Moore JT. Willson TM, et al. Mol Endocrinol. 2002 Jun;16(6):1135-44. doi: 10.1210/mend.16.6.0849. Mol Endocrinol. 2002. PMID: 12040002 Review.

2

Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

Krylova IN, Sablin EP, Moore J, Xu RX, Waitt GM, MacKay JA, Juzumiene D, Bynum JM, Madauss K, Montana V, Lebedeva L, Suzawa M, Williams JD, Williams SP, Guy RK, Thornton JW, Fletterick RJ, Willson TM, Ingraham HA. Krylova IN, et al. Among authors: willson tm. Cell. 2005 Feb 11;120(3):343-55. doi: 10.1016/j.cell.2005.01.024. Cell. 2005. PMID: 15707893

3

Identification of small molecule agonists of the orphan nuclear receptors liver receptor homolog-1 and steroidogenic factor-1.

Whitby RJ, Dixon S, Maloney PR, Delerive P, Goodwin BJ, Parks DJ, Willson TM. Whitby RJ, et al. Among authors: willson tm. J Med Chem. 2006 Nov 16;49(23):6652-5. doi: 10.1021/jm060990k. J Med Chem. 2006. PMID: 17154495

4

Progress towards a public chemogenomic set for protein kinases and a call for contributions.

Drewry DH, Wells CI, Andrews DM, Angell R, Al-Ali H, Axtman AD, Capuzzi SJ, Elkins JM, Ettmayer P, Frederiksen M, Gileadi O, Gray N, Hooper A, Knapp S, Laufer S, Luecking U, Michaelides M, Müller S, Muratov E, Denny RA, Saikatendu KS, Treiber DK, Zuercher WJ, Willson TM. Drewry DH, et al. Among authors: willson tm. PLoS One. 2017 Aug 2;12(8):e0181585. doi: 10.1371/journal.pone.0181585. eCollection 2017. PLoS One. 2017. PMID: 28767711 Free PMC article.

5

Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma.

Agostini M, Gurnell M, Savage DB, Wood EM, Smith AG, Rajanayagam O, Garnes KT, Levinson SH, Xu HE, Schwabe JW, Willson TM, O'Rahilly S, Chatterjee VK. Agostini M, et al. Among authors: willson tm. Endocrinology. 2004 Apr;145(4):1527-38. doi: 10.1210/en.2003-1271. Epub 2003 Dec 4. Endocrinology. 2004. PMID: 14657011

6

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity.

Watkins RE, Wisely GB, Moore LB, Collins JL, Lambert MH, Williams SP, Willson TM, Kliewer SA, Redinbo MR. Watkins RE, et al. Among authors: willson tm. Science. 2001 Jun 22;292(5525):2329-33. doi: 10.1126/science.1060762. Epub 2001 Jun 14. Science. 2001. PMID: 11408620

7

Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages.

Whitney KD, Watson MA, Goodwin B, Galardi CM, Maglich JM, Wilson JG, Willson TM, Collins JL, Kliewer SA. Whitney KD, et al. Among authors: willson tm. J Biol Chem. 2001 Nov 23;276(47):43509-15. doi: 10.1074/jbc.M106155200. Epub 2001 Aug 23. J Biol Chem. 2001. PMID: 11546778

8

Synthesis and biological activity of L-tyrosine-based PPARgamma agonists with reduced molecular weight.

Liu KG, Lambert MH, Ayscue AH, Henke BR, Leesnitzer LM, Oliver WR Jr, Plunket KD, Xu HE, Sternbach DD, Willson TM. Liu KG, et al. Among authors: willson tm. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3111-3. doi: 10.1016/s0960-894x(01)00649-7. Bioorg Med Chem Lett. 2001. PMID: 11720854

9

Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes.

Maglich JM, Sluder A, Guan X, Shi Y, McKee DD, Carrick K, Kamdar K, Willson TM, Moore JT. Maglich JM, et al. Among authors: willson tm. Genome Biol. 2001;2(8):RESEARCH0029. doi: 10.1186/gb-2001-2-8-research0029. Epub 2001 Jul 24. Genome Biol. 2001. PMID: 11532213 Free PMC article.

10

Identification of a series of oxadiazole-substituted alpha-isopropoxy phenylpropanoic acids with activity on PPARalpha, PPARgamma, and PPARdelta.

Liu KG, Smith JS, Ayscue AH, Henke BR, Lambert MH, Leesnitzer LM, Plunket KD, Willson TM, Sternbach DD. Liu KG, et al. Among authors: willson tm. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2385-8. doi: 10.1016/s0960-894x(01)00458-9. Bioorg Med Chem Lett. 2001. PMID: 11527737

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