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Identification and characterization of the factor H and FHL-1 binding complement regulator-acquiring surface protein 1 of the Lyme disease spirochete Borrelia spielmanii sp. nov.
Herzberger P, Siegel C, Skerka C, Fingerle V, Schulte-Spechtel U, Wilske B, Brade V, Zipfel PF, Wallich R, Kraiczy P. Herzberger P, et al. Among authors: wilske b. Int J Med Microbiol. 2009 Feb;299(2):141-54. doi: 10.1016/j.ijmm.2008.06.005. Epub 2008 Aug 15. Int J Med Microbiol. 2009. PMID: 18706858
Human pathogenic Borrelia spielmanii sp. nov. resists complement-mediated killing by direct binding of immune regulators factor H and factor H-like protein 1.
Herzberger P, Siegel C, Skerka C, Fingerle V, Schulte-Spechtel U, van Dam A, Wilske B, Brade V, Zipfel PF, Wallich R, Kraiczy P. Herzberger P, et al. Among authors: wilske b. Infect Immun. 2007 Oct;75(10):4817-25. doi: 10.1128/IAI.00532-07. Epub 2007 Jul 16. Infect Immun. 2007. PMID: 17635869 Free PMC article.
Osp17, a novel immunodominant outer surface protein of Borrelia afzelii: recombinant expression in Escherichia coli and its use as a diagnostic antigen for serodiagnosis of Lyme borreliosis.
Jauris-Heipke S, Rössle B, Wanner G, Habermann C, Rössler D, Fingerle V, Lehnert G, Lobentanzer R, Pradel I, Hillenbrand B, Schulte-Spechtel U, Wilske B. Jauris-Heipke S, et al. Among authors: wilske b. Med Microbiol Immunol. 1999 May;187(4):213-9. doi: 10.1007/s004300050095. Med Microbiol Immunol. 1999. PMID: 10363678
An improved recombinant IgG immunoblot for serodiagnosis of Lyme borreliosis.
Wilske B, Habermann C, Fingerle V, Hillenbrand B, Jauris-Heipke S, Lehnert G, Pradel I, Rössler D, Schulte-Spechtel U. Wilske B, et al. Med Microbiol Immunol. 1999 Dec;188(3):139-44. doi: 10.1007/s004300050116. Med Microbiol Immunol. 1999. PMID: 10776844
We have previously described the use of the following recombinant antigens for serodiagnostic immunoblots: p83/100, p39, OspC and p41 (flagellin) internal fragment [Wilske et al. (1993) Med Microbiol Immunol 182:255-270; Rossler et al. (1997) J Clin Microbiol 35:2752-2758] …
We have previously described the use of the following recombinant antigens for serodiagnostic immunoblots: p83/100, p39, OspC and p41 (flage …
Sequence analysis of ospA genes shows homogeneity within Borrelia burgdorferi sensu stricto and Borrelia afzelii strains but reveals major subgroups within the Borrelia garinii species.
Will G, Jauris-Heipke S, Schwab E, Busch U, Rössler D, Soutschek E, Wilske B, Preac-Mursic V. Will G, et al. Among authors: wilske b. Med Microbiol Immunol. 1995 Aug;184(2):73-80. doi: 10.1007/BF00221390. Med Microbiol Immunol. 1995. PMID: 7500914
However, we found evidence for intragenic recombination by cluster analysis of ospA sequence data. Accordance of ospA genotype 1 strains with B. burgdorferi sensu stricto and ospA genotype 2 strains with B. afzelii, as well as the ospA genotype strains 3-7 with B
However, we found evidence for intragenic recombination by cluster analysis of ospA sequence data. Accordance of ospA genotype 1 strains wit …
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