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The interleukin-8 pathway in cancer.
Waugh DJ, Wilson C. Waugh DJ, et al. Among authors: wilson c. Clin Cancer Res. 2008 Nov 1;14(21):6735-41. doi: 10.1158/1078-0432.CCR-07-4843. Clin Cancer Res. 2008. PMID: 18980965 Review.
The induction of IL-8 signaling activates multiple upstream signaling pathways that (a) impinge on gene expression via regulation of numerous transcription factor activities, (b) modulate the cellular proteome at the level of translation, and/or (c) effect the organization …
The induction of IL-8 signaling activates multiple upstream signaling pathways that (a) impinge on gene expression via regulation of numerou …
FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma.
Ramsey MR, Wilson C, Ory B, Rothenberg SM, Faquin W, Mills AA, Ellisen LW. Ramsey MR, et al. Among authors: wilson c. J Clin Invest. 2013 Aug;123(8):3525-38. doi: 10.1172/JCI68899. Epub 2013 Jul 8. J Clin Invest. 2013. PMID: 23867503 Free PMC article.
Constitutive and treatment-induced CXCL8-signalling selectively modulates the efficacy of anti-metabolite therapeutics in metastatic prostate cancer.
Wilson C, Maxwell PJ, Longley DB, Wilson RH, Johnston PG, Waugh DJ. Wilson C, et al. Among authors: wilson rh. PLoS One. 2012;7(5):e36545. doi: 10.1371/journal.pone.0036545. Epub 2012 May 9. PLoS One. 2012. PMID: 22590561 Free PMC article.
Interleukin-8 signaling attenuates TRAIL- and chemotherapy-induced apoptosis through transcriptional regulation of c-FLIP in prostate cancer cells.
Wilson C, Wilson T, Johnston PG, Longley DB, Waugh DJ. Wilson C, et al. Among authors: wilson t. Mol Cancer Ther. 2008 Sep;7(9):2649-61. doi: 10.1158/1535-7163.MCT-08-0148. Mol Cancer Ther. 2008. PMID: 18790747
Administration of recombinant human IL-8 was shown to increase the mRNA transcript levels and expression of c-FLIP(L) and c-FLIP(S), two isoforms of the endogenous caspase-8 inhibitor. Pretreatment with the CXCR2 antagonist AZ10397767 significantly attenuated IL-8-i …
Administration of recombinant human IL-8 was shown to increase the mRNA transcript levels and expression of c-FLIP(L) and c-FL …
Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis.
Wilson C, Purcell C, Seaton A, Oladipo O, Maxwell PJ, O'Sullivan JM, Wilson RH, Johnston PG, Waugh DJ. Wilson C, et al. Among authors: wilson rh. J Pharmacol Exp Ther. 2008 Dec;327(3):746-59. doi: 10.1124/jpet.108.143826. Epub 2008 Sep 9. J Pharmacol Exp Ther. 2008. PMID: 18780829
Multi-faceted roles for CXC-chemokines in prostate cancer progression.
Waugh DJ, Wilson C, Seaton A, Maxwell PJ. Waugh DJ, et al. Among authors: wilson c. Front Biosci. 2008 May 1;13:4595-604. doi: 10.2741/3025. Front Biosci. 2008. PMID: 18508531 Review.
Interleukin-8 signaling promotes translational regulation of cyclin D in androgen-independent prostate cancer cells.
MacManus CF, Pettigrew J, Seaton A, Wilson C, Maxwell PJ, Berlingeri S, Purcell C, McGurk M, Johnston PG, Waugh DJ. MacManus CF, et al. Among authors: wilson c. Mol Cancer Res. 2007 Jul;5(7):737-48. doi: 10.1158/1541-7786.MCR-07-0032. Epub 2007 Jul 2. Mol Cancer Res. 2007. PMID: 17606477
Our results indicate that IL-8 signaling (a) regulates cyclin D1 expression at the level of translation, (b) regulates the activation of proteins associated with the translation of capped and 5'-oligopyrimidine tract transcripts, and (c) activates signal transduction pathw …
Our results indicate that IL-8 signaling (a) regulates cyclin D1 expression at the level of translation, (b) regulates the activation of pro …
Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation.
Seaton A, Scullin P, Maxwell PJ, Wilson C, Pettigrew J, Gallagher R, O'Sullivan JM, Johnston PG, Waugh DJ. Seaton A, et al. Among authors: wilson c. Carcinogenesis. 2008 Jun;29(6):1148-56. doi: 10.1093/carcin/bgn109. Epub 2008 May 16. Carcinogenesis. 2008. PMID: 18487223
BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling.
Pajni-Underwood S, Wilson CP, Elder C, Mishina Y, Lewandoski M. Pajni-Underwood S, et al. Among authors: wilson cp. Development. 2007 Jun;134(12):2359-68. doi: 10.1242/dev.001677. Development. 2007. PMID: 17537800
A microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinoma.
Ory B, Ramsey MR, Wilson C, Vadysirisack DD, Forster N, Rocco JW, Rothenberg SM, Ellisen LW. Ory B, et al. Among authors: wilson c. J Clin Invest. 2011 Feb;121(2):809-20. doi: 10.1172/JCI43897. J Clin Invest. 2011. PMID: 21293058 Free PMC article.
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