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1,093 results
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Modulation of hepatitis C virus RNA accumulation and translation by DDX6 and miR-122 are mediated by separate mechanisms.
Huys A, Thibault PA, Wilson JA. Huys A, et al. Among authors: wilson ja. PLoS One. 2013 Jun 24;8(6):e67437. doi: 10.1371/journal.pone.0067437. Print 2013. PLoS One. 2013. PMID: 23826300 Free PMC article.
RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells.
Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG, Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. Wilson JA, et al. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2783-8. doi: 10.1073/pnas.252758799. Epub 2003 Feb 19. Proc Natl Acad Sci U S A. 2003. PMID: 12594341 Free PMC article.
Hepatitis C virus replicons escape RNA interference induced by a short interfering RNA directed against the NS5b coding region.
Wilson JA, Richardson CD. Wilson JA, et al. J Virol. 2005 Jun;79(11):7050-8. doi: 10.1128/JVI.79.11.7050-7058.2005. J Virol. 2005. PMID: 15890944 Free PMC article.
Future promise of siRNA and other nucleic acid based therapeutics for the treatment of chronic HCV.
Wilson JA, Richardson CD. Wilson JA, et al. Infect Disord Drug Targets. 2006 Mar;6(1):43-56. doi: 10.2174/187152606776056689. Infect Disord Drug Targets. 2006. PMID: 16787303 Review.
Replication of subgenomic hepatitis C virus replicons in mouse fibroblasts is facilitated by deletion of interferon regulatory factor 3 and expression of liver-specific microRNA 122.
Lin LT, Noyce RS, Pham TN, Wilson JA, Sisson GR, Michalak TI, Mossman KL, Richardson CD. Lin LT, et al. Among authors: wilson ja. J Virol. 2010 Sep;84(18):9170-80. doi: 10.1128/JVI.00559-10. Epub 2010 Jun 30. J Virol. 2010. PMID: 20592082 Free PMC article.
Human Ago2 is required for efficient microRNA 122 regulation of hepatitis C virus RNA accumulation and translation.
Wilson JA, Zhang C, Huys A, Richardson CD. Wilson JA, et al. J Virol. 2011 Mar;85(5):2342-50. doi: 10.1128/JVI.02046-10. Epub 2010 Dec 22. J Virol. 2011. PMID: 21177824 Free PMC article.
Requirements for human Dicer and TRBP in microRNA-122 regulation of HCV translation and RNA abundance.
Zhang C, Huys A, Thibault PA, Wilson JA. Zhang C, et al. Among authors: wilson ja. Virology. 2012 Nov 25;433(2):479-88. doi: 10.1016/j.virol.2012.08.039. Epub 2012 Sep 19. Virology. 2012. PMID: 22999255
MicroRNA-122-dependent and -independent replication of Hepatitis C Virus in Hep3B human hepatoma cells.
Thibault PA, Huys A, Dhillon P, Wilson JA. Thibault PA, et al. Among authors: wilson ja. Virology. 2013 Feb 5;436(1):179-90. doi: 10.1016/j.virol.2012.11.007. Epub 2012 Dec 13. Virology. 2013. PMID: 23245472
Targeting miRNAs to treat Hepatitis C Virus infections and liver pathology: Inhibiting the virus and altering the host.
Thibault PA, Wilson JA. Thibault PA, et al. Among authors: wilson ja. Pharmacol Res. 2013 Sep;75:48-59. doi: 10.1016/j.phrs.2013.03.004. Epub 2013 Mar 27. Pharmacol Res. 2013. PMID: 23541631 Review.
Modulation of GB virus B RNA abundance by microRNA-122: dependence on and escape from microRNA-122 restriction.
Sagan SM, Sarnow P, Wilson JA. Sagan SM, et al. Among authors: wilson ja. J Virol. 2013 Jul;87(13):7338-47. doi: 10.1128/JVI.00378-13. Epub 2013 Apr 24. J Virol. 2013. PMID: 23616647 Free PMC article.
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