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Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: focus on orexin targets involved in control of food and water intake.
Bäckberg M, Hervieu G, Wilson S, Meister B. Bäckberg M, et al. Eur J Neurosci. 2002 Jan;15(2):315-28. doi: 10.1046/j.0953-816x.2001.01859.x. Eur J Neurosci. 2002. PMID: 11849298
Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord.
Cutler DJ, Morris R, Sheridhar V, Wattam TA, Holmes S, Patel S, Arch JR, Wilson S, Buckingham RE, Evans ML, Leslie RA, Williams G. Cutler DJ, et al. Peptides. 1999 Dec;20(12):1455-70. doi: 10.1016/s0196-9781(99)00157-6. Peptides. 1999. PMID: 10698122
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.
Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M. Sakurai T, et al. Cell. 1998 Feb 20;92(4):573-85. doi: 10.1016/s0092-8674(00)80949-6. Cell. 1998. PMID: 9491897
Interactions between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat.
Wang Q, Bing C, Al-Barazanji K, Mossakowaska DE, Wang XM, McBay DL, Neville WA, Taddayon M, Pickavance L, Dryden S, Thomas ME, McHale MT, Gloyer IS, Wilson S, Buckingham R, Arch JR, Trayhurn P, Williams G. Wang Q, et al. Diabetes. 1997 Mar;46(3):335-41. doi: 10.2337/diab.46.3.335. Diabetes. 1997. PMID: 9032086
We investigated whether leptin's short-term effects on energy balance are mediated by inhibition of the NPY neurons. Recombinant murine leptin (11 microg) injected into the lateral ventricle of fasted adult Wistar rats inhibited food intake by 20-25% between 2 and 6 h afte …
We investigated whether leptin's short-term effects on energy balance are mediated by inhibition of the NPY neurons. Recombinant muri …
Orexin expression and function: glucocorticoid manipulation, stress, and feeding studies.
Ford GK, Al-Barazanji KA, Wilson S, Jones DN, Harbuz MS, Jessop DS. Ford GK, et al. Endocrinology. 2005 Sep;146(9):3724-31. doi: 10.1210/en.2005-0496. Epub 2005 Jun 16. Endocrinology. 2005. PMID: 15961555
Hypoglycemia activates orexin neurons and selectively increases hypothalamic orexin-B levels: responses inhibited by feeding and possibly mediated by the nucleus of the solitary tract.
Cai XJ, Evans ML, Lister CA, Leslie RA, Arch JR, Wilson S, Williams G. Cai XJ, et al. Diabetes. 2001 Jan;50(1):105-12. doi: 10.2337/diabetes.50.1.105. Diabetes. 2001. PMID: 11147774
The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation.
Milasta S, Evans NA, Ormiston L, Wilson S, Lefkowitz RJ, Milligan G. Milasta S, et al. Biochem J. 2005 May 1;387(Pt 3):573-84. doi: 10.1042/BJ20041745. Biochem J. 2005. PMID: 15683363 Free PMC article.
Food restriction selectively increases hypothalamic orexin-B levels in lactating rats.
Cai XJ, Denis R, Vernon RG, Clapham JC, Wilson S, Arch JR, Williams G. Cai XJ, et al. Regul Pept. 2001 Mar 2;97(2-3):163-8. doi: 10.1016/s0167-0115(00)00209-3. Regul Pept. 2001. PMID: 11164952
Central orexin-A activates hypothalamic-pituitary-adrenal axis and stimulates hypothalamic corticotropin releasing factor and arginine vasopressin neurones in conscious rats.
Al-Barazanji KA, Wilson S, Baker J, Jessop DS, Harbuz MS. Al-Barazanji KA, et al. J Neuroendocrinol. 2001 May;13(5):421-4. doi: 10.1046/j.1365-2826.2001.00655.x. J Neuroendocrinol. 2001. PMID: 11328451
Hypothalamic orexin expression: modulation by blood glucose and feeding.
Cai XJ, Widdowson PS, Harrold J, Wilson S, Buckingham RE, Arch JR, Tadayyon M, Clapham JC, Wilding J, Williams G. Cai XJ, et al. Diabetes. 1999 Nov;48(11):2132-7. doi: 10.2337/diabetes.48.11.2132. Diabetes. 1999. PMID: 10535445
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