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Genetics of poliovirus.
Wimmer E, Hellen CU, Cao X. Wimmer E, et al. Annu Rev Genet. 1993;27:353-436. doi: 10.1146/ Annu Rev Genet. 1993. PMID: 8122908 Review. No abstract available.
Eradicating polio: A balancing act.
Agol V, Cello J, Chumakov K, Ehrenfeld E, Wimmer E. Agol V, et al. Science. 2016 Jan 22;351(6271):348. doi: 10.1126/science.351.6271.348-b. Science. 2016. PMID: 26798005 No abstract available.
Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization.
Le Nouën C, Brock LG, Luongo C, McCarty T, Yang L, Mehedi M, Wimmer E, Mueller S, Collins PL, Buchholz UJ, DiNapoli JM. Le Nouën C, et al. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13169-74. doi: 10.1073/pnas.1411290111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157129 Free PMC article.
Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine.
Sanders BP, de Los Rios Oakes I, van Hoek V, Bockstal V, Kamphuis T, Uil TG, Song Y, Cooper G, Crawt LE, Martín J, Zahn R, Lewis J, Wimmer E, Custers JH, Schuitemaker H, Cello J, Edo-Matas D. Sanders BP, et al. PLoS Pathog. 2016 Mar 31;12(3):e1005483. doi: 10.1371/journal.ppat.1005483. eCollection 2016 Mar. PLoS Pathog. 2016. PMID: 27032093 Free PMC article.
Binding of glutathione to enterovirus capsids is essential for virion morphogenesis.
Thibaut HJ, van der Linden L, Jiang P, Thys B, Canela MD, Aguado L, Rombaut B, Wimmer E, Paul A, Pérez-Pérez MJ, van Kuppeveld FJ, Neyts J. Thibaut HJ, et al. PLoS Pathog. 2014 Apr 10;10(4):e1004039. doi: 10.1371/journal.ppat.1004039. eCollection 2014 Apr. PLoS Pathog. 2014. PMID: 24722756 Free PMC article.
Brunenders: a partially attenuated historic poliovirus type I vaccine strain.
Sanders BP, Liu Y, Brandjes A, van Hoek V, de Los Rios Oakes I, Lewis J, Wimmer E, Custers JHHV, Schuitemaker H, Cello J, Edo-Matas D. Sanders BP, et al. J Gen Virol. 2015 Sep;96(9):2614-2622. doi: 10.1099/vir.0.000197. Epub 2015 May 26. J Gen Virol. 2015. PMID: 26018960
Production of high titer attenuated poliovirus strains on the serum-free PER.C6(®) cell culture platform for the generation of safe and affordable next generation IPV.
Sanders BP, Oakes Ide L, van Hoek V, Liu Y, Marissen W, Minor PD, Wimmer E, Schuitemaker H, Custers JH, Macadam A, Cello J, Edo-Matas D. Sanders BP, et al. Vaccine. 2015 Nov 27;33(48):6611-6. doi: 10.1016/j.vaccine.2015.10.091. Epub 2015 Nov 1. Vaccine. 2015. PMID: 26529068
Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes.
Song Y, Gorbatsevych O, Liu Y, Mugavero J, Shen SH, Ward CB, Asare E, Jiang P, Paul AV, Mueller S, Wimmer E. Song Y, et al. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8731-E8740. doi: 10.1073/pnas.1714385114. Epub 2017 Sep 25. Proc Natl Acad Sci U S A. 2017. PMID: 28973853 Free PMC article.
Picornavirus morphogenesis.
Jiang P, Liu Y, Ma HC, Paul AV, Wimmer E. Jiang P, et al. Microbiol Mol Biol Rev. 2014 Sep;78(3):418-37. doi: 10.1128/MMBR.00012-14. Microbiol Mol Biol Rev. 2014. PMID: 25184560 Free PMC article. Review.
Poliomyelitis in transgenic mice expressing CD155 under the control of the Tage4 promoter after oral and parenteral poliovirus inoculation.
Khan S, Toyoda H, Linehan M, Iwasaki A, Nomoto A, Bernhardt G, Cello J, Wimmer E. Khan S, et al. J Gen Virol. 2014 Aug;95(Pt 8):1668-1676. doi: 10.1099/vir.0.064535-0. Epub 2014 Apr 30. J Gen Virol. 2014. PMID: 24784416 Free PMC article.
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