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Intra-abdominal pressure, sagittal abdominal diameter and obesity comorbidity.
Sugerman H, Windsor A, Bessos M, Wolfe L. Sugerman H, et al. J Intern Med. 1997 Jan;241(1):71-9. doi: 10.1046/j.1365-2796.1997.89104000.x. J Intern Med. 1997. PMID: 9042096
W:H ratio was not a reliable indicator of intra-abdominal pressure for women who often have both peripheral and central obesity. ...
W:H ratio was not a reliable indicator of intra-abdominal pressure for women who often have both peripheral and central obesity. ...
Effects of surgically induced weight loss on urinary bladder pressure, sagittal abdominal diameter and obesity co-morbidity.
Sugerman H, Windsor A, Bessos M, Kellum J, Reines H, DeMaria E. Sugerman H, et al. Int J Obes Relat Metab Disord. 1998 Mar;22(3):230-5. doi: 10.1038/sj.ijo.0800574. Int J Obes Relat Metab Disord. 1998. PMID: 9539191
A dual-binding antibody to E- and L-selectin attenuates sepsis-induced lung injury.
Ridings PC, Windsor AC, Jutila MA, Blocher CR, Fisher BJ, Sholley MM, Sugerman HJ, Fowler AA 3rd. Ridings PC, et al. Am J Respir Crit Care Med. 1995 Jul;152(1):247-53. doi: 10.1164/ajrccm.152.1.7541277. Am J Respir Crit Care Med. 1995. PMID: 7541277
We studied the effects of pretreatment with a dual-binding porcine anti-E- and anti-L-selectin monoclonal antibody (EL-246) on a porcine model of sepsis-induced lung injury. ...Group 2 (septic) received a 1-h infusion of Pseudomonas aeruginosa. Group 3 (EL-24 …
We studied the effects of pretreatment with a dual-binding porcine anti-E- and anti-L-selectin monoclonal antibody (EL-246) on a
Delayed tumor necrosis factor alpha blockade attenuates pulmonary dysfunction and metabolic acidosis associated with experimental gram-negative sepsis.
Windsor AC, Mullen PG, Walsh CJ, Fisher BJ, Blocher CR, Jesmok G, Fowler AA 3rd, Sugerman HJ. Windsor AC, et al. Arch Surg. 1994 Jan;129(1):80-9. doi: 10.1001/archsurg.1994.01420250092012. Arch Surg. 1994. PMID: 8279944
INTERVENTION: Anesthetized swine were made septic with a 1-hour infusion of live Pseudomonas aeruginosa, following which a treatment group received an infusion of anti-TNF-alpha monoclonal antibody (5 mg/kg). ...Furthermore, anti-TNF-alpha treatment reversed septic …
INTERVENTION: Anesthetized swine were made septic with a 1-hour infusion of live Pseudomonas aeruginosa, following which a tre …
Sepsis-induced acute lung injury is attenuated by selectin blockade following the onset of sepsis.
Ridings PC, Bloomfield GL, Holloway S, Windsor AC, Jutila MA, Fowler AA 3rd, Sugerman HJ. Ridings PC, et al. Arch Surg. 1995 Nov;130(11):1199-208. doi: 10.1001/archsurg.1995.01430110057011. Arch Surg. 1995. PMID: 7487463
OBJECTIVE: To determine the effect of infusion with a dual-binding antibody to E- and L-selectin, EL-246, in a postonset model of sepsis. ...Untreated animals with sepsis (n = 8) received a 1-hour intravenous infusion of live Pseudomonas aeruginosa. Animals t …
OBJECTIVE: To determine the effect of infusion with a dual-binding antibody to E- and L-selectin, EL-246, in a postonset model …
Beneficial cardiopulmonary effects of pentoxifylline in experimental sepsis are lost once septic shock is established.
Ridings PC, Windsor AC, Sugerman HJ, Kennedy E, Sholley MM, Blocher CR, Fisher BJ, Fowler AA. Ridings PC, et al. Arch Surg. 1994 Nov;129(11):1144-52. doi: 10.1001/archsurg.1994.01420350042004. Arch Surg. 1994. PMID: 7979946
OBJECTIVE: To determine the effects of pretreatment and posttreatment with pentoxifylline in a porcine model of gram-negative sepsis. ...Group 2 swine (sepsis, n = 8) received a 1-hour infusion of Pseudomonas aeruginosa. Groups 3, 4, and 5 swine received the P aerug …
OBJECTIVE: To determine the effects of pretreatment and posttreatment with pentoxifylline in a porcine model of gram-negative sepsis. …
Differential activation of alveolar, pulmonary arterial, and systemic arterial neutrophils demonstrates the existence of distinct neutrophil subpopulations in experimental sepsis.
Windsor AC, Carey PD, Sugerman HJ, Mullen PG, Walsh CJ, Fisher BJ, Blocher CR, Fowler AA 3rd. Windsor AC, et al. Shock. 1994 Jan;1(1):53-9. doi: 10.1097/00024382-199401000-00010. Shock. 1994. PMID: 7743329
Swine were anesthetized and ventilated, and given a 1-h infusion of live Pseudomonas aeruginosa. PA, SA, and ALV PMNs were isolated at 0 and 5 h. ...These data corroborate a dissociation between two PMN functions in sepsis. O2- generation was reduced across the lung …
Swine were anesthetized and ventilated, and given a 1-h infusion of live Pseudomonas aeruginosa. PA, SA, and ALV PMNs were isolated a …
Circulating ICAM-1 is increased in septic shock.
Sessler CN, Windsor AC, Schwartz M, Watson L, Fisher BJ, Sugerman HJ, Fowler AA 3rd. Sessler CN, et al. Am J Respir Crit Care Med. 1995 May;151(5):1420-7. doi: 10.1164/ajrccm.151.5.7735595. Am J Respir Crit Care Med. 1995. PMID: 7735595
Adhesion molecules play a critical role in the interaction of circulating neutrophils with vascular endothelium during inflammation. ...There was a positive correlation (r = 0.50, p = 0.009) between Day-1 cICAM-1 measurements and severity of shock as determined by t …
Adhesion molecules play a critical role in the interaction of circulating neutrophils with vascular endothelium during inflammation. …
Pulmonary artery endothelial cell function in swine pseudomonas sepsis.
Kadletz M, Dignan RJ, Mullen PG, Windsor AC, Sugerman HJ, Wechsler AS. Kadletz M, et al. J Surg Res. 1996 Jan;60(1):186-92. doi: 10.1006/jsre.1996.0030. J Surg Res. 1996. PMID: 8592413
A substantial increase in pulmonary vascular resistance is associated with sepsis and its sequelae (sepsis syndrome and septic shock). ...Septic animals received a 1-hr infusion of live Pseudomonas aeruginosa (n = 11), and the control cohort received 0.9% NaCl (n =
A substantial increase in pulmonary vascular resistance is associated with sepsis and its sequelae (sepsis syndrome and septic shock)
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