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Multi-omics links IL-6 trans-signalling with neutrophil extracellular trap formation and Haemophilus infection in COPD.
Winslow S, Odqvist L, Diver S, Riise R, Abdillahi S, Wingren C, Lindmark H, Wellner A, Lundin S, Yrlid L, Ax E, Djukanovic R, Sridhar S, Higham A, Singh D, Southworth T, Brightling CE, Olsson HK, Jevnikar Z. Winslow S, et al. Among authors: wingren c. Eur Respir J. 2021 Oct 14;58(4):2003312. doi: 10.1183/13993003.03312-2020. Print 2021 Oct. Eur Respir J. 2021. PMID: 33766947 Free article.
HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD.
Horndahl J, Svärd R, Berntsson P, Wingren C, Li J, Abdillahi SM, Ghosh B, Capodanno E, Chan J, Ripa L, Åstrand A, Sidhaye VK, Collins M. Horndahl J, et al. Among authors: wingren c. PLoS One. 2022 Oct 12;17(10):e0266310. doi: 10.1371/journal.pone.0266310. eCollection 2022. PLoS One. 2022. PMID: 36223404 Free PMC article.
Selective Janus kinase 1 inhibition resolves inflammation and restores hair growth offering a viable treatment option for alopecia areata.
Mattsson J, Israelsson E, Björhall K, Yrlid LF, Thörn K, Thorén A, Toledo EA, Jinton L, Öberg L, Wingren C, Tapani S, Jackson SG, Skogberg G, Lundqvist AJ, Hendrickx R, Cavallin A, Österlund T, Grimster NP, Nilsson M, Åstrand A. Mattsson J, et al. Among authors: wingren c. Skin Health Dis. 2023 Jan 29;3(3):e209. doi: 10.1002/ski2.209. eCollection 2023 Jun. Skin Health Dis. 2023. PMID: 37275428 Free PMC article.
INEXAS: A Phase 2 Randomized Trial of On-demand Inhaled Interferon Beta-1a in Severe Asthmatics.
McCrae C, Olsson M, Gustafson P, Malmgren A, Aurell M, Fagerås M, Da Silva CA, Cavallin A, Paraskos J, Karlsson K, Wingren C, Monk P, Marsden R, Harrison T. McCrae C, et al. Among authors: wingren c. Clin Exp Allergy. 2021 Feb;51(2):273-283. doi: 10.1111/cea.13765. Epub 2020 Nov 3. Clin Exp Allergy. 2021. PMID: 33091192 Free PMC article. Clinical Trial.
The discovery of a selective and potent A2a agonist with extended lung retention.
Åstrand AB, Lamm Bergström E, Zhang H, Börjesson L, Söderdahl T, Wingren C, Jansson AH, Smailagic A, Johansson C, Bladh H, Shamovsky I, Tunek A, Drmota T. Åstrand AB, et al. Among authors: wingren c. Pharmacol Res Perspect. 2015 Jun;3(3):e00134. doi: 10.1002/prp2.134. Epub 2015 May 4. Pharmacol Res Perspect. 2015. PMID: 26236482 Free PMC article.
Preclinical evaluation of the epithelial sodium channel inhibitor AZD5634 and implications on human translation.
Åstrand A, Libby EF, Shei RJ, Lever JEP, Kaza N, Adewale AT, Boitet E, Edwards L, Hemmerling M, Root J, Lindberg B, Wingren C, Malmgren A, Sabater J, Rowe SM. Åstrand A, et al. Among authors: wingren c. Am J Physiol Lung Cell Mol Physiol. 2022 Nov 1;323(5):L536-L547. doi: 10.1152/ajplung.00454.2021. Epub 2022 Sep 13. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 36098422 Free PMC article.
130 results