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The SRPHK1 outcome measure for cocaine-dependence trials combines self-report, urine benzoylecgonine levels, and the concordance between the two to determine a cocaine-use status for each study day.
Somoza E, Somoza P, Lewis D, Li SH, Winhusen T, Chiang N, Vocci F, Horn P, Elkashef A. Somoza E, et al. Drug Alcohol Depend. 2008 Jan 11;93(1-2):132-40. doi: 10.1016/j.drugalcdep.2007.09.007. Epub 2007 Oct 29. Drug Alcohol Depend. 2008. PMID: 18029115 Clinical Trial.
A double-blind, placebo-controlled trial of reserpine for the treatment of cocaine dependence.
Winhusen T, Somoza E, Sarid-Segal O, Goldsmith RJ, Harrer JM, Coleman FS, Kahn R, Osman S, Mezinskis J, Li SH, Lewis D, Afshar M, Ciraulo DA, Horn P, Montgomery MA, Elkashef A. Winhusen T, et al. Drug Alcohol Depend. 2007 Dec 1;91(2-3):205-12. doi: 10.1016/j.drugalcdep.2007.05.021. Epub 2007 Jul 12. Drug Alcohol Depend. 2007. PMID: 17628352 Free PMC article. Clinical Trial.
A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence.
Winhusen T, Somoza E, Ciraulo DA, Harrer JM, Goldsmith RJ, Grabowski J, Coleman FS, Mindrum G, Kahn R, Osman S, Mezinskis J, Li SH, Lewis D, Horn P, Montgomery MA, Elkashef A. Winhusen T, et al. Drug Alcohol Depend. 2007 Dec 1;91(2-3):141-8. doi: 10.1016/j.drugalcdep.2007.05.028. Epub 2007 Jul 16. Drug Alcohol Depend. 2007. PMID: 17629631 Clinical Trial.
Impulsivity is associated with treatment non-completion in cocaine- and methamphetamine-dependent patients but differs in nature as a function of stimulant-dependence diagnosis.
Winhusen T, Lewis D, Adinoff B, Brigham G, Kropp F, Donovan DM, Seamans CL, Hodgkins CC, Dicenzo JC, Botero CL, Jones DR, Somoza E. Winhusen T, et al. J Subst Abuse Treat. 2013 May-Jun;44(5):541-7. doi: 10.1016/j.jsat.2012.12.005. Epub 2013 Jan 8. J Subst Abuse Treat. 2013. PMID: 23305820 Free PMC article. Clinical Trial.
105 results