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9 results
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Post-prenylation-processing enzymes as new targets in oncogenesis.
Winter-Vann AM, Casey PJ. Winter-Vann AM, et al. Nat Rev Cancer. 2005 May;5(5):405-12. doi: 10.1038/nrc1612. Nat Rev Cancer. 2005. PMID: 15864282 Review.
Targeting Ras signaling through inhibition of carboxyl methylation: an unexpected property of methotrexate.
Winter-Vann AM, Kamen BA, Bergo MO, Young SG, Melnyk S, James SJ, Casey PJ. Winter-Vann AM, et al. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6529-34. doi: 10.1073/pnas.1135239100. Epub 2003 May 15. Proc Natl Acad Sci U S A. 2003. PMID: 12750467 Free PMC article.
A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.
Winter-Vann AM, Baron RA, Wong W, dela Cruz J, York JD, Gooden DM, Bergo MO, Young SG, Toone EJ, Casey PJ. Winter-Vann AM, et al. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4336-41. doi: 10.1073/pnas.0408107102. Proc Natl Acad Sci U S A. 2005. PMID: 15784746 Free PMC article.
A micromere induction signal is activated by beta-catenin and acts through notch to initiate specification of secondary mesenchyme cells in the sea urchin embryo.
McClay DR, Peterson RE, Range RC, Winter-Vann AM, Ferkowicz MJ. McClay DR, et al. Among authors: winter vann am. Development. 2000 Dec;127(23):5113-22. Development. 2000. PMID: 11060237 Free article.
Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo.
Abell AN, Rivera-Perez JA, Cuevas BD, Uhlik MT, Sather S, Johnson NL, Minton SK, Lauder JM, Winter-Vann AM, Nakamura K, Magnuson T, Vaillancourt RR, Heasley LE, Johnson GL. Abell AN, et al. Among authors: winter vann am. Mol Cell Biol. 2005 Oct;25(20):8948-59. doi: 10.1128/MCB.25.20.8948-8959.2005. Mol Cell Biol. 2005. PMID: 16199873 Free PMC article.
Integrated activation of MAP3Ks balances cell fate in response to stress.
Winter-Vann AM, Johnson GL. Winter-Vann AM, et al. J Cell Biochem. 2007 Nov 1;102(4):848-58. doi: 10.1002/jcb.21522. J Cell Biochem. 2007. PMID: 17786929 Review.
MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.
Cuevas BD, Winter-Vann AM, Johnson NL, Johnson GL. Cuevas BD, et al. Among authors: winter vann am. Oncogene. 2006 Aug 17;25(36):4998-5010. doi: 10.1038/sj.onc.1209507. Epub 2006 Mar 27. Oncogene. 2006. PMID: 16568086
Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1.
Schlitzer M, Winter-Vann A, Casey PJ. Schlitzer M, et al. Bioorg Med Chem Lett. 2001 Feb 12;11(3):425-7. doi: 10.1016/s0960-894x(00)00685-5. Bioorg Med Chem Lett. 2001. PMID: 11212127
Heterologous gene expression in a membrane-protein-specific system.
Turner GJ, Reusch R, Winter-Vann AM, Martinez L, Betlach MC. Turner GJ, et al. Among authors: winter vann am. Protein Expr Purif. 1999 Nov;17(2):312-23. doi: 10.1006/prep.1999.1110. Protein Expr Purif. 1999. PMID: 10545281