Wirth DF - Search Results

1

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.

Antonova-Koch Y, Meister S, Abraham M, Luth MR, Ottilie S, Lukens AK, Sakata-Kato T, Vanaerschot M, Owen E, Jado JC, Maher SP, Calla J, Plouffe D, Zhong Y, Chen K, Chaumeau V, Conway AJ, McNamara CW, Ibanez M, Gagaring K, Serrano FN, Eribez K, Taggard CM, Cheung AL, Lincoln C, Ambachew B, Rouillier M, Siegel D, Nosten F, Kyle DE, Gamo FJ, Zhou Y, Llinás M, Fidock DA, Wirth DF, Burrows J, Campo B, Winzeler EA. Antonova-Koch Y, et al. Among authors: wirth df. Science. 2018 Dec 7;362(6419):eaat9446. doi: 10.1126/science.aat9446. Science. 2018. PMID: 30523084 Free PMC article.

2

Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum.

Wilson CM, Serrano AE, Wasley A, Bogenschutz MP, Shankar AH, Wirth DF. Wilson CM, et al. Among authors: wirth df. Science. 1989 Jun 9;244(4909):1184-6. doi: 10.1126/science.2658061. Science. 1989. PMID: 2658061

3

Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand.

Wilson CM, Volkman SK, Thaithong S, Martin RK, Kyle DE, Milhous WK, Wirth DF. Wilson CM, et al. Among authors: wirth df. Mol Biochem Parasitol. 1993 Jan;57(1):151-60. doi: 10.1016/0166-6851(93)90252-s. Mol Biochem Parasitol. 1993. PMID: 8426608

4

Serial analysis of gene expression (SAGE) in Plasmodium falciparum: application of the technique to A-T rich genomes.

Munasinghe A, Patankar S, Cook BP, Madden SL, Martin RK, Kyle DE, Shoaibi A, Cummings LM, Wirth DF. Munasinghe A, et al. Among authors: wirth df. Mol Biochem Parasitol. 2001 Mar;113(1):23-34. doi: 10.1016/s0166-6851(00)00378-9. Mol Biochem Parasitol. 2001. PMID: 11254951

5

Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae.

Emerson LR, Nau ME, Martin RK, Kyle DE, Vahey M, Wirth DF. Emerson LR, et al. Among authors: wirth df. Antimicrob Agents Chemother. 2002 Mar;46(3):787-96. doi: 10.1128/AAC.46.3.787-796.2002. Antimicrob Agents Chemother. 2002. PMID: 11850263 Free PMC article.

6

The paradoxical population genetics of Plasmodium falciparum.

Hartl DL, Volkman SK, Nielsen KM, Barry AE, Day KP, Wirth DF, Winzeler EA. Hartl DL, et al. Among authors: wirth df. Trends Parasitol. 2002 Jun;18(6):266-72. doi: 10.1016/s1471-4922(02)02268-7. Trends Parasitol. 2002. PMID: 12036741 Review.

7

Excess polymorphisms in genes for membrane proteins in Plasmodium falciparum.

Volkman SK, Hartl DL, Wirth DF, Nielsen KM, Choi M, Batalov S, Zhou Y, Plouffe D, Le Roch KG, Abagyan R, Winzeler EA. Volkman SK, et al. Among authors: wirth df. Science. 2002 Oct 4;298(5591):216-8. doi: 10.1126/science.1075642. Science. 2002. PMID: 12364807

8

Point mutations in the pfcrt and pfmdr-1 genes of Plasmodium falciparum and clinical response to chloroquine, among malaria patients from Nigeria.

Happi TC, Thomas SM, Gbotosho GO, Falade CO, Akinboye DO, Gerena L, Hudson T, Sowunmi A, Kyle DE, Milhous W, Wirth DF, Oduola AM. Happi TC, et al. Among authors: wirth df. Ann Trop Med Parasitol. 2003 Jul;97(5):439-51. doi: 10.1179/000349803235002489. Ann Trop Med Parasitol. 2003. PMID: 12930607

9

In vivo transcriptional profiling of Plasmodium falciparum.

Daily JP, Le Roch KG, Sarr O, Fang X, Zhou Y, Ndir O, Mboup S, Sultan A, Winzeler EA, Wirth DF. Daily JP, et al. Among authors: wirth df. Malar J. 2004 Aug 5;3:30. doi: 10.1186/1475-2875-3-30. Malar J. 2004. PMID: 15296511 Free PMC article.

10

In vivo transcriptome of Plasmodium falciparum reveals overexpression of transcripts that encode surface proteins.

Daily JP, Le Roch KG, Sarr O, Ndiaye D, Lukens A, Zhou Y, Ndir O, Mboup S, Sultan A, Winzeler EA, Wirth DF. Daily JP, et al. Among authors: wirth df. J Infect Dis. 2005 Apr 1;191(7):1196-203. doi: 10.1086/428289. Epub 2005 Feb 28. J Infect Dis. 2005. PMID: 15747257 Free PMC article.

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