Wise DR - Search Results

1

Glutamine addiction: a new therapeutic target in cancer.

Wise DR, Thompson CB. Wise DR, et al. Trends Biochem Sci. 2010 Aug;35(8):427-33. doi: 10.1016/j.tibs.2010.05.003. Trends Biochem Sci. 2010. PMID: 20570523 Free PMC article. Review.

2

Preparation and characterization of L-[5-11C]-glutamine for metabolic imaging of tumors.

Qu W, Oya S, Lieberman BP, Ploessl K, Wang L, Wise DR, Divgi CR, Chodosh LA, Thompson CB, Kung HF. Qu W, et al. Among authors: wise dr. J Nucl Med. 2012 Jan;53(1):98-105. doi: 10.2967/jnumed.111.093831. Epub 2011 Dec 15. J Nucl Med. 2012. PMID: 22173839 Free article.

3

PET imaging of glutaminolysis in tumors by 18F-(2S,4R)4-fluoroglutamine.

Lieberman BP, Ploessl K, Wang L, Qu W, Zha Z, Wise DR, Chodosh LA, Belka G, Thompson CB, Kung HF. Lieberman BP, et al. Among authors: wise dr. J Nucl Med. 2011 Dec;52(12):1947-55. doi: 10.2967/jnumed.111.093815. Epub 2011 Nov 15. J Nucl Med. 2011. PMID: 22095958

4

ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.

Qing G, Li B, Vu A, Skuli N, Walton ZE, Liu X, Mayes PA, Wise DR, Thompson CB, Maris JM, Hogarty MD, Simon MC. Qing G, et al. Among authors: wise dr. Cancer Cell. 2012 Nov 13;22(5):631-44. doi: 10.1016/j.ccr.2012.09.021. Cancer Cell. 2012. PMID: 23153536 Free PMC article.

5

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.

Wise DR, Ward PS, Shay JE, Cross JR, Gruber JJ, Sachdeva UM, Platt JM, DeMatteo RG, Simon MC, Thompson CB. Wise DR, et al. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19611-6. doi: 10.1073/pnas.1117773108. Epub 2011 Nov 21. Proc Natl Acad Sci U S A. 2011. PMID: 22106302 Free PMC article.

6

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.

Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, Thompson CB. Ward PS, et al. Among authors: wise dr. Cancer Cell. 2010 Mar 16;17(3):225-34. doi: 10.1016/j.ccr.2010.01.020. Epub 2010 Feb 18. Cancer Cell. 2010. PMID: 20171147 Free PMC article.

7

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.

Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB. Wise DR, et al. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18782-7. doi: 10.1073/pnas.0810199105. Epub 2008 Nov 24. Proc Natl Acad Sci U S A. 2008. PMID: 19033189 Free PMC article.

8

Facile synthesis [5-(13)C-4-(2)H(2)]-L-glutamine for hyperpolarized MRS imaging of cancer cell metabolism.

Qu W, Zha Z, Lieberman BP, Mancuso A, Stetz M, Rizzi R, Ploessl K, Wise D, Thompson C, Kung HF. Qu W, et al. Acad Radiol. 2011 Aug;18(8):932-9. doi: 10.1016/j.acra.2011.05.002. Epub 2011 Jun 11. Acad Radiol. 2011. PMID: 21658976

9

Cutaneous vulvar metastases in a patient with anal squamous cell carcinoma.

Wise DR, Kim BS, Ferenczi K, Rosenbach M. Wise DR, et al. Cutis. 2013 Mar;91(3):125-6. Cutis. 2013. PMID: 23617081

10

Synthesis of optically pure 4-fluoro-glutamines as potential metabolic imaging agents for tumors.

Qu W, Zha Z, Ploessl K, Lieberman BP, Zhu L, Wise DR, Thompson CB, Kung HF. Qu W, et al. Among authors: wise dr. J Am Chem Soc. 2011 Feb 2;133(4):1122-33. doi: 10.1021/ja109203d. Epub 2010 Dec 29. J Am Chem Soc. 2011. PMID: 21190335

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