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Impact of various conditions on the efficacy of dual carbapenem therapy against KPC-producing Klebsiella pneumoniae.
Wiskirchen DE, Crandon JL, Nicolau DP. Wiskirchen DE, et al. Int J Antimicrob Agents. 2013 Jun;41(6):582-5. doi: 10.1016/j.ijantimicag.2013.02.015. Epub 2013 Apr 21. Int J Antimicrob Agents. 2013. PMID: 23611306
Inpatient antibiotic resistance: Everyone's problem.
Wiskirchen DE, Wu U, Summa M, Perrin A. Wiskirchen DE, et al. J Fam Pract. 2018 Feb;67(2):E1-E11. J Fam Pract. 2018. PMID: 29400898
Comparative pharmacokinetics, pharmacodynamics, and tolerability of ertapenem 1 gram/day administered as a rapid 5-minute infusion versus the standard 30-minute infusion in healthy adult volunteers.
Wiskirchen DE, Housman ST, Quintiliani R, Nicolau DP, Kuti JL. Wiskirchen DE, et al. Pharmacotherapy. 2013 Mar;33(3):266-74. doi: 10.1002/phar.1197. Epub 2013 Feb 11. Pharmacotherapy. 2013. PMID: 23400916 Clinical Trial.
In vitro pharmacodynamics of vancomycin and cefazolin alone and in combination against methicillin-resistant Staphylococcus aureus.
Hagihara M, Wiskirchen DE, Kuti JL, Nicolau DP. Hagihara M, et al. Antimicrob Agents Chemother. 2012 Jan;56(1):202-7. doi: 10.1128/AAC.05473-11. Epub 2011 Oct 17. Antimicrob Agents Chemother. 2012. PMID: 22006007 Free PMC article.
Determination of tissue penetration and pharmacokinetics of linezolid in patients with diabetic foot infections using in vivo microdialysis.
Wiskirchen DE, Shepard A, Kuti JL, Nicolau DP. Wiskirchen DE, et al. Antimicrob Agents Chemother. 2011 Sep;55(9):4170-5. doi: 10.1128/AAC.00445-11. Epub 2011 Jun 27. Antimicrob Agents Chemother. 2011. PMID: 21709078 Free PMC article. Clinical Trial.
In vivo efficacy of a human-simulated regimen of ceftaroline combined with NXL104 against extended-spectrum-beta-lactamase (ESBL)-producing and non-ESBL-producing Enterobacteriaceae.
Wiskirchen DE, Crandon JL, Furtado GH, Williams G, Nicolau DP. Wiskirchen DE, et al. Antimicrob Agents Chemother. 2011 Jul;55(7):3220-5. doi: 10.1128/AAC.00024-11. Epub 2011 Apr 25. Antimicrob Agents Chemother. 2011. PMID: 21518838 Free PMC article.
Tissue penetration and pharmacokinetics of tigecycline in diabetic patients with chronic wound infections described by using in vivo microdialysis.
Bulik CC, Wiskirchen DE, Shepard A, Sutherland CA, Kuti JL, Nicolau DP. Bulik CC, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5209-13. doi: 10.1128/AAC.01051-10. Epub 2010 Oct 4. Antimicrob Agents Chemother. 2010. PMID: 20921312 Free PMC article. Clinical Trial.
In vitro pharmacodynamics of simulated pulmonary exposures of tigecycline alone and in combination against Klebsiella pneumoniae isolates producing a KPC carbapenemase.
Wiskirchen DE, Koomanachai P, Nicasio AM, Nicolau DP, Kuti JL. Wiskirchen DE, et al. Antimicrob Agents Chemother. 2011 Apr;55(4):1420-7. doi: 10.1128/AAC.01253-10. Epub 2011 Jan 31. Antimicrob Agents Chemother. 2011. PMID: 21282442 Free PMC article.
Antibiotic stewardship: The FP's role.
Wiskirchen DE, Summa M, Perrin A. Wiskirchen DE, et al. J Fam Pract. 2016 Dec;65(12):876-885. J Fam Pract. 2016. PMID: 28149970 Review.
Efficacy of humanized carbapenem and ceftazidime regimens against Enterobacteriaceae producing OXA-48 carbapenemase in a murine infection model.
Wiskirchen DE, Nordmann P, Crandon JL, Nicolau DP. Wiskirchen DE, et al. Antimicrob Agents Chemother. 2014;58(3):1678-83. doi: 10.1128/AAC.01947-13. Epub 2013 Dec 30. Antimicrob Agents Chemother. 2014. PMID: 24379200 Free PMC article.
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