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The skinny on neurotrophins.
Wisse BE, Schwartz MW. Wisse BE, et al. Nat Neurosci. 2003 Jul;6(7):655-6. doi: 10.1038/nn0703-655. Nat Neurosci. 2003. PMID: 12830151 No abstract available.
Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus.
Campos CA, Bowen AJ, Han S, Wisse BE, Palmiter RD, Schwartz MW. Campos CA, et al. Among authors: wisse be. Nat Neurosci. 2017 Jul;20(7):934-942. doi: 10.1038/nn.4574. Epub 2017 Jun 5. Nat Neurosci. 2017. PMID: 28581479 Free PMC article.
Reversal of cancer anorexia by blockade of central melanocortin receptors in rats.
Wisse BE, Frayo RS, Schwartz MW, Cummings DE. Wisse BE, et al. Endocrinology. 2001 Aug;142(8):3292-301. doi: 10.1210/endo.142.8.8324. Endocrinology. 2001. PMID: 11459770
This suggests that new targets for the treatment of cancer anorexia may be found in the melanocortin pathways....
This suggests that new targets for the treatment of cancer anorexia may be found in the melanocortin pathways....
Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses.
Thaler JP, Choi SJ, Sajan MP, Ogimoto K, Nguyen HT, Matsen M, Benoit SC, Wisse BE, Farese RV, Schwartz MW. Thaler JP, et al. Endocrinology. 2009 Dec;150(12):5362-72. doi: 10.1210/en.2009-0509. Epub 2009 Oct 9. Endocrinology. 2009. PMID: 19819945 Free PMC article.
Acutely decreased thermoregulatory energy expenditure or decreased activity energy expenditure both acutely reduce food intake in mice.
Kaiyala KJ, Morton GJ, Thaler JP, Meek TH, Tylee T, Ogimoto K, Wisse BE. Kaiyala KJ, et al. PLoS One. 2012;7(8):e41473. doi: 10.1371/journal.pone.0041473. Epub 2012 Aug 22. PLoS One. 2012. PMID: 22936977 Free PMC article.
Despite the suggestion that reduced energy expenditure may be a key contributor to the obesity pandemic, few studies have tested whether acutely reduced energy expenditure is associated with a compensatory reduction in food intake. ...
Despite the suggestion that reduced energy expenditure may be a key contributor to the obesity pandemic, few studies have tested whet …
Lipopolysaccharide-induced lung injury is independent of serum vitamin D concentration.
Klaff LS, Gill SE, Wisse BE, Mittelsteadt K, Matute-Bello G, Chen P, Altemeier WA. Klaff LS, et al. PLoS One. 2012;7(11):e49076. doi: 10.1371/journal.pone.0049076. Epub 2012 Nov 19. PLoS One. 2012. PMID: 23185294 Free PMC article.
Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia.
German JP, Thaler JP, Wisse BE, Oh-I S, Sarruf DA, Matsen ME, Fischer JD, Taborsky GJ Jr, Schwartz MW, Morton GJ. German JP, et al. Endocrinology. 2011 Feb;152(2):394-404. doi: 10.1210/en.2010-0890. Epub 2010 Dec 15. Endocrinology. 2011. PMID: 21159853 Free PMC article.
Identification of a physiological role for leptin in the regulation of ambulatory activity and wheel running in mice.
Morton GJ, Kaiyala KJ, Fisher JD, Ogimoto K, Schwartz MW, Wisse BE. Morton GJ, et al. Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E392-401. doi: 10.1152/ajpendo.00546.2010. Epub 2010 Nov 9. Am J Physiol Endocrinol Metab. 2011. PMID: 21062956 Free PMC article.
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