Witkiewicz AK[Author] - Search Results

Year	Number of Results
1999	1
2005	3
2007	1
2008	3
2009	20
2010	20
2011	21
2012	15
2013	7
2014	11
2015	8
2016	10
2017	8
2018	6
2019	8
2020	10
2021	3

1

The history and future of targeting cyclin-dependent kinases in cancer therapy.

Asghar U, Witkiewicz AK, Turner NC, Knudsen ES. Asghar U, et al. Among authors: witkiewicz ak. Nat Rev Drug Discov. 2015 Feb;14(2):130-46. doi: 10.1038/nrd4504. Nat Rev Drug Discov. 2015. PMID: 25633797 Free PMC article. Review.

2

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.

Bryant KL, Stalnecker CA, Zeitouni D, Klomp JE, Peng S, Tikunov AP, Gunda V, Pierobon M, Waters AM, George SD, Tomar G, Papke B, Hobbs GA, Yan L, Hayes TK, Diehl JN, Goode GD, Chaika NV, Wang Y, Zhang GF, Witkiewicz AK, Knudsen ES, Petricoin EF 3rd, Singh PK, Macdonald JM, Tran NL, Lyssiotis CA, Ying H, Kimmelman AC, Cox AD, Der CJ. Bryant KL, et al. Among authors: witkiewicz ak. Nat Med. 2019 Apr;25(4):628-640. doi: 10.1038/s41591-019-0368-8. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833752 Free PMC article.

3

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Sousa CM, et al. Among authors: witkiewicz ak. Nature. 2016 Aug 25;536(7617):479-83. doi: 10.1038/nature19084. Epub 2016 Aug 10. Nature. 2016. PMID: 27509858 Free PMC article.

4

Cell Cycle and Beyond: Exploiting New RB1 Controlled Mechanisms for Cancer Therapy.

Knudsen ES, Pruitt SC, Hershberger PA, Witkiewicz AK, Goodrich DW. Knudsen ES, et al. Among authors: witkiewicz ak. Trends Cancer. 2019 May;5(5):308-324. doi: 10.1016/j.trecan.2019.03.005. Epub 2019 Apr 30. Trends Cancer. 2019. PMID: 31174843 Free PMC article. Review.

5

Acetate dependence of tumors.

Comerford SA, Huang Z, Du X, Wang Y, Cai L, Witkiewicz AK, Walters H, Tantawy MN, Fu A, Manning HC, Horton JD, Hammer RE, McKnight SL, Tu BP. Comerford SA, et al. Among authors: witkiewicz ak. Cell. 2014 Dec 18;159(7):1591-602. doi: 10.1016/j.cell.2014.11.020. Cell. 2014. PMID: 25525877 Free PMC article.

6

p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.

Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM. Guiley KZ, et al. Among authors: witkiewicz ak. Science. 2019 Dec 13;366(6471):eaaw2106. doi: 10.1126/science.aaw2106. Science. 2019. PMID: 31831640 Free PMC article.

7

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.

Witkiewicz AK, McMillan EA, Balaji U, Baek G, Lin WC, Mansour J, Mollaee M, Wagner KU, Koduru P, Yopp A, Choti MA, Yeo CJ, McCue P, White MA, Knudsen ES. Witkiewicz AK, et al. Nat Commun. 2015 Apr 9;6:6744. doi: 10.1038/ncomms7744. Nat Commun. 2015. PMID: 25855536 Free PMC article.

8

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism.

Vaseva AV, Blake DR, Gilbert TSK, Ng S, Hostetter G, Azam SH, Ozkan-Dagliyan I, Gautam P, Bryant KL, Pearce KH, Herring LE, Han H, Graves LM, Witkiewicz AK, Knudsen ES, Pecot CV, Rashid N, Houghton PJ, Wennerberg K, Cox AD, Der CJ. Vaseva AV, et al. Among authors: witkiewicz ak. Cancer Cell. 2018 Nov 12;34(5):807-822.e7. doi: 10.1016/j.ccell.2018.10.001. Cancer Cell. 2018. PMID: 30423298 Free PMC article.

9

The Strange Case of CDK4/6 Inhibitors: Mechanisms, Resistance, and Combination Strategies.

Knudsen ES, Witkiewicz AK. Knudsen ES, et al. Among authors: witkiewicz ak. Trends Cancer. 2017 Jan;3(1):39-55. doi: 10.1016/j.trecan.2016.11.006. Trends Cancer. 2017. PMID: 28303264 Free PMC article. Review.

10

Chronic expression of p16^INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation.

Azazmeh N, Assouline B, Winter E, Ruppo S, Nevo Y, Maly A, Meir K, Witkiewicz AK, Cohen J, Rizou SV, Pikarsky E, Luxenburg C, Gorgoulis VG, Ben-Porath I. Azazmeh N, et al. Among authors: witkiewicz ak. Nat Commun. 2020 Jun 1;11(1):2711. doi: 10.1038/s41467-020-16475-3. Nat Commun. 2020. PMID: 32483135 Free PMC article.

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