Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

36 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Enhancing antibody Fc heterodimer formation through electrostatic steering effects: applications to bispecific molecules and monovalent IgG.
Gunasekaran K, Pentony M, Shen M, Garrett L, Forte C, Woodward A, Ng SB, Born T, Retter M, Manchulenko K, Sweet H, Foltz IN, Wittekind M, Yan W. Gunasekaran K, et al. Among authors: Wittekind M. J Biol Chem. 2010 Jun 18;285(25):19637-46. doi: 10.1074/jbc.M110.117382. Epub 2010 Apr 16. J Biol Chem. 2010. PMID: 20400508 Free PMC article.
Common structural changes accompany the functional inactivation of HPr by seryl phosphorylation or by serine to aspartate substitution.
Wittekind M, Reizer J, Deutscher J, Saier MH, Klevit RE. Wittekind M, et al. Biochemistry. 1989 Dec 26;28(26):9908-12. doi: 10.1021/bi00452a005. Biochemistry. 1989. PMID: 2515891
., Saier, M. H., Stewart, G. C., Peterkofsky, A., & Reddy, P. (1989) EMBO J. 8, 2111-2120]. Two-dimensional spectra of these two modified proteins display nearly identical proton chemical shifts that differ significantly from those observed in the spectra of the unphosphorylated, wild-type protein and of functionally active HPr mutants. ...
., Saier, M. H., Stewart, G. C., Peterkofsky, A., & Reddy, P. (1989) EMBO J. 8, 2111-2120]. Two-dimensional spectra of these two …
Backbone and side chain dynamics of uncomplexed human adipocyte and muscle fatty acid-binding proteins.
Constantine KL, Friedrichs MS, Wittekind M, Jamil H, Chu CH, Parker RA, Goldfarb V, Mueller L, Farmer BT 2nd. Constantine KL, et al. Among authors: Wittekind M. Biochemistry. 1998 Jun 2;37(22):7965-80. doi: 10.1021/bi980203o. Biochemistry. 1998. PMID: 9609689
Although highly homologous (65%) and structurally very similar, A-LBP and M-FABP display distinct ligand binding characteristics. Since ligand binding may be influenced by intrinsic protein dynamical properties, we have characterized the backbone and side chain dynamics of uncomplexed (apo) human A-LBP and M-FABP. ...
Although highly homologous (65%) and structurally very similar, A-LBP and M-FABP display distinct ligand binding characteristics. Sin …
The structure of HPr and site-directed mutagenesis.
Waygood EB, Sharma S, Bhanot P, el-Kabbani OA, Delbaere LT, Georges F, Wittekind MG, Klevit RE. Waygood EB, et al. Among authors: Wittekind MG. FEMS Microbiol Rev. 1989 Jun;5(1-2):43-52. doi: 10.1111/j.1574-6968.1989.tb14099.x. FEMS Microbiol Rev. 1989. PMID: 2483820 Review. No abstract available.
Production of stable anti-digoxin Fv in Escherichia coli.
Anthony J, Near R, Wong SL, Iida E, Ernst E, Wittekind M, Haber E, Ng SC. Anthony J, et al. Among authors: Wittekind M. Mol Immunol. 1992 Oct;29(10):1237-47. doi: 10.1016/0161-5890(92)90060-b. Mol Immunol. 1992. PMID: 1528194
The 26-10 VH and VL proteins were cleaved at their mature N-termini and exported into the bacterial periplasm where they could be easily extracted and affinity purified on ouabain-Sepharose. 26-10 Fv bound to digoxin with similar affinity and specificity as the whole 26-10 antibody (Ka for Fv, 1.3 x 10(9) M-1, Ka for IgG, 7 x 10(9) M-1). 26-10 Fv appears to be remarkably stable in comparison with other Fv fragments. ...
The 26-10 VH and VL proteins were cleaved at their mature N-termini and exported into the bacterial periplasm where they could be easily ext …
36 results
Jump to page
Feedback