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Novel optical nanosensors for probing and imaging live cells.
Kneipp J, Kneipp H, Wittig B, Kneipp K. Kneipp J, et al. Nanomedicine. 2010 Apr;6(2):214-26. doi: 10.1016/j.nano.2009.07.009. Epub 2009 Aug 20. Nanomedicine. 2010. PMID: 19699322 Review.
Schistosoma mansoni miracidia transformed by particle bombardment infect Biomphalaria glabrata snails and develop into transgenic sporocysts.
Heyers O, Walduck AK, Brindley PJ, Bleiss W, Lucius R, Dorbic T, Wittig B, Kalinna BH. Heyers O, et al. Exp Parasitol. 2003 Oct;105(2):174-8. doi: 10.1016/j.exppara.2003.11.001. Exp Parasitol. 2003. PMID: 14969695
Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma.
Schmidt-Wolf IG, Finke S, Trojaneck B, Denkena A, Lefterova P, Schwella N, Heuft HG, Prange G, Korte M, Takeya M, Dorbic T, Neubauer A, Wittig B, Huhn D. Schmidt-Wolf IG, et al. Br J Cancer. 1999 Nov;81(6):1009-16. doi: 10.1038/sj.bjc.6690800. Br J Cancer. 1999. PMID: 10576658 Free PMC article. Clinical Trial.
Minimizing side effects of ballistic gene transfer into the murine corneal epithelium.
Zhang EP, Muller A, Schulte F, König MS, Sack F, Junghans C, Wittig B, Hoffmann F. Zhang EP, et al. Graefes Arch Clin Exp Ophthalmol. 2002 Feb;240(2):114-9. doi: 10.1007/s00417-001-0411-5. Graefes Arch Clin Exp Ophthalmol. 2002. PMID: 11931076
A novel minimal-size vector (MIDGE) improves transgene expression in colon carcinoma cells and avoids transfection of undesired DNA.
Schakowski F, Gorschlüter M, Junghans C, Schroff M, Buttgereit P, Ziske C, Schöttker B, König-Merediz SA, Sauerbruch T, Wittig B, Schmidt-Wolf IG. Schakowski F, et al. Mol Ther. 2001 May;3(5 Pt 1):793-800. doi: 10.1006/mthe.2001.0322. Mol Ther. 2001. PMID: 11356084
Ballistic transfer of minimalistic immunologically defined expression constructs for IL4 and CTLA4 into the corneal epithelium in mice after orthotopic corneal allograft transplantation.
König Merediz SA, Zhang EP, Wittig B, Hoffmann F. König Merediz SA, et al. Graefes Arch Clin Exp Ophthalmol. 2000 Aug;238(8):701-7. doi: 10.1007/s004170000144. Graefes Arch Clin Exp Ophthalmol. 2000. PMID: 11011692
Minimal size MIDGE vectors improve transgene expression in vivo.
Schakowski F, Gorschlüter M, Buttgereit P, Märten A, Lilienfeld-Toal MV, Junghans C, Schroff M, König-Merediz SA, Ziske C, Strehl J, Sauerbruch T, Wittig B, Schmidt-Wolf IG. Schakowski F, et al. In Vivo. 2007 Jan-Feb;21(1):17-23. In Vivo. 2007. PMID: 17354609
Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+ CD56+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene.
Finke S, Trojaneck B, Lefterova P, Csipai M, Wagner E, Kircheis R, Neubauer A, Huhn D, Wittig B, Schmidt-Wolf IG. Finke S, et al. Gene Ther. 1998 Jan;5(1):31-9. doi: 10.1038/sj.gt.3300560. Gene Ther. 1998. PMID: 9536262
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