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Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac.
Rehmann H, Rueppel A, Bos JL, Wittinghofer A. Rehmann H, et al. Among authors: wittinghofer a. J Biol Chem. 2003 Jun 27;278(26):23508-14. doi: 10.1074/jbc.M301680200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707263
This protein consists of a regulatory region with a cAMP-binding domain and a catalytic region that mediates the GEF activity. ...L., and Wittinghofer, A. (2003) Nat. Struct. Biol. 10, 26-32). Here we show that mutations of conserved residues in …
This protein consists of a regulatory region with a cAMP-binding domain and a catalytic region that mediates the GEF ac …
316 results