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Year Number of Results
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1996 3
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1,130 results

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Wogonin and its analogs for the prevention and treatment of cancer: A systematic review.
Banik K, Khatoon E, Harsha C, Rana V, Parama D, Thakur KK, Bishayee A, Kunnumakkara AB. Banik K, et al. Phytother Res. 2022 May;36(5):1854-1883. doi: 10.1002/ptr.7386. Epub 2022 Jan 31. Phytother Res. 2022. PMID: 35102626 Review.
The roots of this plant contain bioactive compounds, such as wogonin (WOG), wogonoside, baicalein, and baicalin. The aim of this article is to evaluate the therapeutic potential and mechanisms of action of WOG against different cancers. ...
The roots of this plant contain bioactive compounds, such as wogonin (WOG), wogonoside, baicalein, and baicalin. The aim of this arti …
Wogonin protects glomerular podocytes by targeting Bcl-2-mediated autophagy and apoptosis in diabetic kidney disease.
Liu XQ, Jiang L, Li YY, Huang YB, Hu XR, Zhu W, Wang X, Wu YG, Meng XM, Qi XM. Liu XQ, et al. Acta Pharmacol Sin. 2022 Jan;43(1):96-110. doi: 10.1038/s41401-021-00721-5. Epub 2021 Jul 12. Acta Pharmacol Sin. 2022. PMID: 34253875 Free PMC article.
We demonstrated that wogonin directly bound to Bcl-2 in MPC5 cells. In HG-treated MPC5 cells, knockdown of Bcl-2 abolished the beneficial effects of wogonin, whereas overexpression of Bcl-2 mimicked the protective effects of wogonin. ...Wogonin may be …
We demonstrated that wogonin directly bound to Bcl-2 in MPC5 cells. In HG-treated MPC5 cells, knockdown of Bcl-2 abolished the benefi …
Integrated bioinformatics and network pharmacology to identify the therapeutic target and molecular mechanisms of Huangqin decoction on ulcerative Colitis.
Wu Y, Liu X, Li G. Wu Y, et al. Sci Rep. 2022 Jan 7;12(1):159. doi: 10.1038/s41598-021-03980-8. Sci Rep. 2022. PMID: 34997010 Free PMC article.
According to ZINC15 database, quercetin (ZINC4175638), baicalein (ZINC3871633), and wogonin (ZINC899093) recognized as key compounds of HQD on ulcerative colitis. ...
According to ZINC15 database, quercetin (ZINC4175638), baicalein (ZINC3871633), and wogonin (ZINC899093) recognized as key compounds …
Can Wogonin be Used in Controlling Diabetic Cardiomyopathy?
Khan S, Kamal MA. Khan S, et al. Curr Pharm Des. 2019;25(19):2171-2177. doi: 10.2174/1381612825666190708173108. Curr Pharm Des. 2019. PMID: 31298148 Review.
Wogonin has long been used as an active anti-cancer drug in Chinese medicine practice. In recent past wogonin has shown to possess notable anti-inflammatory, and anti-allergic properties. ...
Wogonin has long been used as an active anti-cancer drug in Chinese medicine practice. In recent past wogonin has shown to pos …
Wogonin inhibits latent HIV-1 reactivation by downregulating histone crotonylation.
Zhang H, Cai J, Li C, Deng L, Zhu H, Huang T, Zhao J, Zhou J, Deng K, Hong Z, Xia J. Zhang H, et al. Phytomedicine. 2023 Jul 25;116:154855. doi: 10.1016/j.phymed.2023.154855. Epub 2023 May 3. Phytomedicine. 2023. PMID: 37172478
PURPOSE: The current study aimed to explore whether wogonin can suppress latent HIV-1 reactivation and the mechanism of wogonin in inhibiting proviral HIV-1 transcription. ...Wogonin exhibited low cytotoxicity and long-lasting inhibition of HIV-1 transcriptio …
PURPOSE: The current study aimed to explore whether wogonin can suppress latent HIV-1 reactivation and the mechanism of wogonin …
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions.
Tuli HS, Rath P, Chauhan A, Parashar G, Parashar NC, Joshi H, Rani I, Ramniwas S, Aggarwal D, Kumar M, Rana R. Tuli HS, et al. Exp Biol Med (Maywood). 2023 May;248(9):820-828. doi: 10.1177/15353702231179961. Epub 2023 Jun 30. Exp Biol Med (Maywood). 2023. PMID: 37387217 Free PMC article. Review.
This plant's abundance of flavones (wogonoside) and their related aglycones (wogonin) is responsible for many of its pharmacologic effects. A significant ingredient in S. baicalensis that has been the subject of the most research is wogonin. ...It also emphasizes th …
This plant's abundance of flavones (wogonoside) and their related aglycones (wogonin) is responsible for many of its pharmacologic ef …
Potential therapeutic and pharmacological effects of Wogonin: an updated review.
Huynh DL, Ngau TH, Nguyen NH, Tran GB, Nguyen CT. Huynh DL, et al. Mol Biol Rep. 2020 Dec;47(12):9779-9789. doi: 10.1007/s11033-020-05972-9. Epub 2020 Nov 9. Mol Biol Rep. 2020. PMID: 33165817 Review.
Traditionally, the root of Scutellaria baicalensis is widely used as Chinese herbal medicine and contains several major bioactive compounds such as Wogonin, Scutellarein, Baicalein, and Baicalin. Experimental and clinical evidence has been proving that Wogonin exhib …
Traditionally, the root of Scutellaria baicalensis is widely used as Chinese herbal medicine and contains several major bioactive compounds …
Combination of Irinotecan and Melatonin with the Natural Compounds Wogonin and Celastrol for Colon Cancer Treatment.
Radajewska A, Moreira H, Bęben D, Siwiela O, Szyjka A, Gębczak K, Nowak P, Frąszczak J, Emhemmed F, Muller CD, Barg E. Radajewska A, et al. Int J Mol Sci. 2023 May 31;24(11):9544. doi: 10.3390/ijms24119544. Int J Mol Sci. 2023. PMID: 37298495 Free PMC article.
The strongest effect on the induction of cancer cell death was observed for the combination of irinotecan with celastrol (1.25 M) or wogonin (50 M) and for the combination of melatonin (2000 M) with celastrol (1.25 M) or wogonin (50 M). ...Compared with single-drug …
The strongest effect on the induction of cancer cell death was observed for the combination of irinotecan with celastrol (1.25 M) or wogo …
Wogonin attenuates the pathogenicity of Streptococcus pneumoniae by double-target inhibition of Pneumolysin and Sortase A.
Gu K, Ding L, Wang Z, Sun Y, Sun X, Yang W, Sun H, Tian Y, Wang Z, Sun L. Gu K, et al. J Cell Mol Med. 2023 Feb;27(4):563-575. doi: 10.1111/jcmm.17684. Epub 2023 Feb 6. J Cell Mol Med. 2023. PMID: 36747468 Free PMC article.
Consequently, wogonin decreased PLY-mediated cell damage and reduced SrtA-mediated biofilm formation by S. pneumoniae. Furthermore, our data indicated that wogonin did not affect PLY expression but directly altered its oligomerization, leading to reduced activity. . …
Consequently, wogonin decreased PLY-mediated cell damage and reduced SrtA-mediated biofilm formation by S. pneumoniae. Furthermore, o …
Regulation of cell signaling pathways by Wogonin in different cancers: Mechanistic review.
Butt G, Ozbey U, Malik DE, Attar R, Youssef L, Farooqi AA. Butt G, et al. Cell Mol Biol (Noisy-le-grand). 2021 Sep 29;67(2):1-7. doi: 10.14715/cmb/2021.67.2.1. Cell Mol Biol (Noisy-le-grand). 2021. PMID: 34817345 Review.
Although researchers have uncovered pleiotropic role of wogonin in the regulation of different oncogenic signaling cascades but there are visible knowledge gaps in our understanding related to regulation of non-coding RNAs by wogonin. Future studies must converge on …
Although researchers have uncovered pleiotropic role of wogonin in the regulation of different oncogenic signaling cascades but there …
1,130 results