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Acidity generated by the tumor microenvironment drives local invasion.
Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell HH, Ibrahim-Hashim A, Bailey K, Balagurunathan Y, Rothberg JM, Sloane BF, Johnson J, Gatenby RA, Gillies RJ. Estrella V, et al. Among authors: wojtkowiak j. Cancer Res. 2013 Mar 1;73(5):1524-35. doi: 10.1158/0008-5472.CAN-12-2796. Epub 2013 Jan 3. Cancer Res. 2013. PMID: 23288510 Free PMC article.
Autophagy on acid.
Wojtkowiak JW, Gillies RJ. Wojtkowiak JW, et al. Autophagy. 2012 Nov;8(11):1688-9. doi: 10.4161/auto.21501. Epub 2012 Aug 9. Autophagy. 2012. PMID: 22874557 Free PMC article.
Targeting the metabolic microenvironment of tumors.
Bailey KM, Wojtkowiak JW, Hashim AI, Gillies RJ. Bailey KM, et al. Among authors: wojtkowiak jw. Adv Pharmacol. 2012;65:63-107. doi: 10.1016/B978-0-12-397927-8.00004-X. Adv Pharmacol. 2012. PMID: 22959024 Free PMC article. Review.
Mechanisms of buffer therapy resistance.
Bailey KM, Wojtkowiak JW, Cornnell HH, Ribeiro MC, Balagurunathan Y, Hashim AI, Gillies RJ. Bailey KM, et al. Among authors: wojtkowiak jw. Neoplasia. 2014 Apr;16(4):354-64.e1-3. doi: 10.1016/j.neo.2014.04.005. Neoplasia. 2014. PMID: 24862761 Free PMC article.
Application of Evolutionary Principles to Cancer Therapy.
Enriquez-Navas PM, Wojtkowiak JW, Gatenby RA. Enriquez-Navas PM, et al. Cancer Res. 2015 Nov 15;75(22):4675-80. doi: 10.1158/0008-5472.CAN-15-1337. Epub 2015 Nov 2. Cancer Res. 2015. PMID: 26527288 Free PMC article. Review.
Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.
Pilon-Thomas S, Kodumudi KN, El-Kenawi AE, Russell S, Weber AM, Luddy K, Damaghi M, Wojtkowiak JW, Mulé JJ, Ibrahim-Hashim A, Gillies RJ. Pilon-Thomas S, et al. Among authors: wojtkowiak jw. Cancer Res. 2016 Mar 15;76(6):1381-90. doi: 10.1158/0008-5472.CAN-15-1743. Epub 2015 Dec 30. Cancer Res. 2016. PMID: 26719539 Free PMC article.
Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution.
Ibrahim-Hashim A, Robertson-Tessi M, Enriquez-Navas PM, Damaghi M, Balagurunathan Y, Wojtkowiak JW, Russell S, Yoonseok K, Lloyd MC, Bui MM, Brown JS, Anderson ARA, Gillies RJ, Gatenby RA. Ibrahim-Hashim A, et al. Among authors: wojtkowiak jw. Cancer Res. 2017 May 1;77(9):2242-2254. doi: 10.1158/0008-5472.CAN-16-2844. Epub 2017 Mar 1. Cancer Res. 2017. PMID: 28249898 Free PMC article.
43 results